ABSOLUTE STEREOSTRUCTURES OF HOVENIDULCIOSIDES A_1 AND A_2,BIOACTIVE NOVEL TRITERPENE GLYCOSIDES FROM HOVENIAE SEMEN SEU FRUCTUS, THE SEEDS AND FRUIT OF HOVENIA DULCIS THUNB.
スポンサーリンク
概要
- 論文の詳細を見る
Two bioactive novel triterpene glycosides named hovenidulciosides A_1 and A_2 have been isolated from a Chinese natural medicine, Hoveniae Semen Seu Fructus, the seeds and fruit of Hovenia dulcis Thunb. (Rhamnaceae). The absolute stereostructures of hovenidulciosides A_1 and A_2 with a migrated 16,17-seco-dammarane skeleton have been determined on the basis of chemical and physicochemical evidence which included the X-ray crystallographic analysis of the p-bromobenzoate of their common aglycone, hovenidulcigenin A. Hovenidulciosides A_1 and A_2 exhibited inhibitory activity on the histamine release from rat mast cells induced by compound 48/80 or calcium ionophore A-23187.
- 社団法人日本薬学会の論文
- 1995-03-15
著者
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吉川 雅之
Kyoto Pharmaceutical Univ.
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渋谷 博孝
福山大学
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青山 寛
近畿大学薬学部
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村岡 修
Faculty of Pharmaceutical Sciences, Kinki University
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山原 條二
京都薬科大学生薬学教室
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村岡 修
Faculty Of Pharmaceutical Sciences Kinki University
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植田 知彦
Kyoto Pharmaceutical University
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青山 寛
Faculty of Pharmaceutical Sciences, Kinki University
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村田 久司
Kyoto Pharmaceutical University
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下田 博司
Kyoto Pharmaceutical University
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山原 條二
Kyoto Pharmaceutical University
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村上 啓寿
Kyoto Pharmaceutical University
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上野 高裕
Kyoto Pharmaceutical University
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UENO Takahiro
Kyoto Pharmaceutical University
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山原 条二
京都薬大
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植田 知彦
京都薬科大学
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UEMURA Toshiaki
Kyoto Pharmaceutical University
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山原 絛二
Kyoto Pharmaceutical University
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Ueno Takahiro
Department Of Respiratory Diseases Institute Of Clinical Medicine University Of Tsukuba
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Ueno T
Kyoto Pharmaceutical University
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Ueno Takahiro
Graduate Course Of Mechanical Engineering Mie University
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Ueno T
Nippon Institute Of Technology
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村岡 修
近畿大薬:近畿大薬総研
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