ELATOSIDE E, A NEW HYPOGLYCEMIC PRINCIPLE FROM THE ROOT CORTEX OF ARALIA ELATA SEEM. : STRUCTURE-RELATED HYPOGLYCEMIC ACTIVITY OF OLEANOLIC ACID GLYCOSIDES

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概要

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• A new inhibitor named elatosides E (which was shown to affect the elevation of plasma glucose level by oral sugar tolerance test in rats) was isolated from the root cortex of Aralia elata SEEM. together with elatoside F. The structures of elatosides E and F were elucidated on the basis of chemical and physicochemical evidence. The hypoglycemic activities of oleanolic acid and nine oleanolic acid glycosides obtained from the root cortex of Aralia elata heve been examined, and some structure-activity relationships have been found.

• 社団法人日本薬学会の論文
• 1994-06-15

著者

• 原田 英美子

  大阪大 薬

• 原田 英美子

  奈良先端科学技術大学院大学遺伝子教育研究センター

• 吉川 雅之

  Kyoto Pharmaceutical Univ.

• 山原 條二

  京都薬科大学生薬学教室

• 山原 條二

  Kyoto Pharmaceutical University

• 村上 啓寿

  Kyoto Pharmaceutical University

• 原田 英美子

  Kyoto Pharmaceutical University

• 村上 敏之

  Kyoto Pharmaceutical University

• 松田 久司

  Kyoto Pharmaceutical University

• 山原 条二

  京都薬大

• 割石 紀子

  森下仁丹 (株) 研究開発部

• 割石 紀子

  Kyoto Pharmaceutical University

• 山原 絛二

  Kyoto Pharmaceutical University

• 松田 久司

  Kyoto Pharmaceutical Univ.

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