CHEMICAL TRANSFORMATION FROM DIHYDROISOCOUMARIN INTO BENZYLIDENEPHTHALIDE BY USE OF REGIOSPECIFIC OXIDATIVE LACTONIZATION MEDIATED BY COPPER CHLORIDE (II) : SYNTHESES OF THUNBERGINOL F AND HYDRAMACROPHYLLOL A AND B
スポンサーリンク
概要
- 論文の詳細を見る
Oxidative lactonization of 2-carboxystilbene mediated by CuCl_2 proceeded regiospecifically to give the five-membered lactone. By utilizing this lactonization as a key reaction, chemical transformation from dihydroisocoumarine into benzylidenephthalide was accomplished, and it was applied to structural elucidation of two new phthalide, hydramacrophyllols A and B.
- 社団法人日本薬学会の論文
- 1994-03-15
著者
-
原田 英美子
大阪大 薬
-
原田 英美子
奈良先端科学技術大学院大学遺伝子教育研究センター
-
吉川 雅之
Kyoto Pharmaceutical Univ.
-
青山 寛
近畿大学薬学部
-
村岡 修
Faculty of Pharmaceutical Sciences, Kinki University
-
村岡 修
Faculty Of Pharmaceutical Sciences Kinki University
-
青山 寛
Faculty of Pharmaceutical Sciences, Kinki University
-
村上 啓寿
Kyoto Pharmaceutical University
-
原田 英美子
Kyoto Pharmaceutical University
-
矢木 信博
京都薬科大学生薬学教室
-
矢木 信博
Kyoto Pharmaceutical University
-
奥野 安洋
Kyoto Pharmaceutical University
-
村岡 修
近畿大薬:近畿大薬総研
関連論文
- Brazilian Natural Medicines. III. Structures of Triterpene Oligoglycosides and Lipase Inhibitors from Mate, Leaves of Ilex paraguariensis
- Medicinal Flowers. XXVI. Structures of Acylated Oleanane-Type Triterpene Oligoglycosides, Yuchasaponins A, B, C, and D, from the Flower Buds of Camellia oleifera : Gastroprotective, Aldose Reductase Inhibitory, and Radical Scavenging Effects
- タイ産Salacia chinensisの生物活性 : α-グルコシダーゼ阻害活性を指標とした品質評価
- エジプト産ファラオ生薬St. Mary's flowerの美白作用成分 (特集 最近の植物成分の開発動向)
- Medicinal Flowers. XXI. : Structures of Perennisaponins A, B, C, D, E, and F, Acylated Oleanane-Type Triterpene Oligoglycosides, from the Flowers of Bellis perennis
- Effects of Wnt-10b on proliferation and differentiation of adult murine skin-derived CD34 and CD49f double-positive cells(CELL AND TISSUE ENGINEERING)
- 食品薬学:薬食同源の視点から薬用食品を科学する —デイジーフラワーの中性脂質上昇抑制作用サポニン成分—
- 茶花(チャ,Camellia sinensis,花蕾部)の機能性サポニン : Floratheasaponin類の胃保護作用と血糖値上昇抑制作用及びHPLCを用いた定性及び定量分析
- 高等植物のカドミウム耐性機構
- シロイヌナズナのイオウ代謝遺伝子群のジャスモン酸による発現制御
- Medicinal Flowers. XXVII : New Flavanone and Chalcone Glycosides, Arenariumosides I, II, III, and IV, and Tumor Necrosis Factor-α Inhibitors from Everlasting, Flowers of Helichrysum arenarium
- Structures of Acetylated Oleanane-Type Triterpene Saponins, Rarasaponins IV, V, and VI, and Anti-hyperlipidemic Constituents from the Pericarps of Sapindus rarak
- Absolute Stereostructures of Olibanumols A, B, C, H, I, and J from Olibanum, Gum-Resin of Boswellia carterii, and Inhibitors of Nitric Oxide Production in Lipopolysaccharide-Activated Mouse Peritoneal Macrophages
- Medicinal Flowers. XXIV. Chemical Structures and Hepatoprotective Effects of Constituents from Flowers of Hedychium coronarium
- Medicinal Flowers. XXIII. New Taraxastane-Type Triterpene, Punicanolic Acid, with Tumor Necrosis Factor-α Inhibitory Activity from the Flowers of Punica granatum
- Bioactive Constituents from Chinese Natural Medicines. XXXII : Aminopeptidase N and Aldose Reductase Inhibitors from Sinocrassula indica: Structures of Sinocrassosides B_4, B_5, C_1, and D_1-D_3
- Medicinal Foodstuffs. XXXIV. : Structures of New Prenylchalcones and Prenylflavanones with TNF-α and Aminopeptidase N Inhibitory Activities from Boesenbergia rotunda
- Medicinal foodstuffs (33) Gastroprotective principles from Boesenbergia rotunda (zingiberaceae): absolute stereostructures of diels-alder type addition prenylchalcones
- Bioactive Constituents from Chinese Natural Medicines. XXVI : Chemical Structures and Hepatoprotective Effects of Constituents from Roots of Rhodiola sachalinensis
- Bioactive Constituents from Chinese Natural Medicines. XXIV. : Hypoglycemic Effects of Sinocrassula indica in Sugar-Loaded Rats and Genetically Diabetic KK-A^y Mice and Structures of New Acylated Flavonol Glycosides, Sinocrassosides A_1, A_2, B_1, and B_2
- C-17 カンカニクジュヨウ(Cistanche tubulosa)の肝保護作用成分(女性医学・肝,一般演題口演,第24回和漢医薬学会大会 和漢薬の複雑さ-経験知と科学知-)
- C-031(30) タイ天然薬物 (7) : ヒルガオ科 Erycibe expansa の新規フラボノイド成分と肝保護作用
- H-5 薫香生薬"没薬"の一酸化窒素産生抑制テルペノイド成分
- Isolation and characterization of murine hepatocytes following collagenase infusion into left ventricle of heart(CELL AND TISSUE ENGINEERING)
- Apoptosis-Inducing Effects of Sterols from the Dried Powder of Cultured Mycelium of Cordyceps sinensis
- P-50 α-グルコシダーゼ阻害剤,kotalanolの合成研究(ポスター発表の部)
- P-60 α-Glucosidase阻害剤,Salacinol類縁体の合成と構造活性相関(ポスター発表の部)
- ABSOLUTE STEREOSTRUCTURES OF HOVENIDULCIOSIDES A_1 AND A_2,BIOACTIVE NOVEL TRITERPENE GLYCOSIDES FROM HOVENIAE SEMEN SEU FRUCTUS, THE SEEDS AND FRUIT OF HOVENIA DULCIS THUNB.
- Bioactive Constituents from Chinese Natural Medicines. XXIII. Absolute Structures of New Megastigmane Glycosides, Sedumosides A_4, A_5, A_6, H, and I, and Hepatoprotective Megastigmanes from Sedum sarmentosum
- Bioactive Constituents from Chinese Natural Medicines. XXII. Absolute Structures of New Megastigmane Glycosides, Sedumosides E_1, E_2, E_3, F_1, F_2, and G, from Sedum sarmentosum (Crassulaceae)
- Bioactive Saponins and Glycosides. XXVIII. New Triterpene Saponins, Foliatheasaponins I, II, III, IV, and V, from Tencha (the Leaves of Camellia sinensis)
- P-469 ANTI-ALLERGIC AND ANTI-INFLAMMATORY ACTIVITIES OF 1'S-1'-ACETOXYCHAVICOL ACETATE AND RELATED COMPOUNDS
- P-466 ACYLATED PHENETHYLGLYCOSIDES WITH VASORELAXANT ACTIVITY FROM CISTANCHE TUBULOSA
- P-298 SYNTHESIS OF 1,5-ANHYDRO-5-AZA-D-GLUCITOL ANALOGS OF SALACINOL AND THEIR α-GLUCOSIDASE INHIBITORY ACTIVITIES
- Monoterpene Constituents from Cistanche tubulosa : Chemical Structures of Kankanosides A-E and Kankanol
- Inhibitors of Nitric Oxide Production from the Rhizomes of Alpinia galanga : Structures of New 8-9' Linked Neolignans and Sesquineolignan
- Antidiabetogenic constituents from Salacia species(Chemical & Pharmacological study)
- Synthesis of a Nitrogen Analogue of Salacinol and Its α-Glucosidase Inhibitory Activity
- P-86 高脂肪食誘発肥満に及ぼす竹節人参サポニンの作用
- Modulated differentiation of embryonic stem cells into hepatocyte-like cells by coculture with hepatic stellate cells
- Study on Anti-Oketsu Activity of Rhubarb II. Anti-allergic Effects of Stillbene Components from Rhei undulati Rhizoma(Dried Rhizome of Rheum undulatum Cultivated in Korea)
- Bioactive Saponins and Glycosides. I. Senegae Radix. (1) : E-Senegasaponins a and b and Z-Senegasaponins a and b, Their Inhibitory Effect on Alcohol Absorption and Hypoglycemic Activity
- E-SENEGASAPONINS A AND B, Z-SENEGASAPONINS A AND B, Z-SENEGINS II AND III, NEW TYPE INHIBITORS OF ETHANOL ABSORPTION IN RATS FROM SENEGAE RADIX, THE ROOTS OF POLYGALA SENEGA L. VAR LATIFOLIA TORREY ET GRAY
- Medicinal Foodstuffs. I. Hypoglycemic Constituents from a Garnish Foodstuff "Taranome, " the Young Shoot of Aralia elata SEEM. : Elatosides G, H, I, J, and K
- Chemical Constituents of Chinese Natural Medicine, Morindae Radix, the Dried Roots of Morinda officinalis How : Structures of Morindolide and Morofficinaloside
- RHODIOCYANOSIDES A AND B, NEW ANTIALLERGIC CYANOGLYCOSIDES FROM CHINESE NATURAL MEDICINE "SI LIE HONG JING TIAN", THE UNDERGROUND PART OF PHODIOLA QUADRIFIDA (PALL.) FISCH. ET MEY.
- Hepatoprotective and Antioxidative Properties of Salacia reticulata : Preventive Effects of Phenolic Constituents on CCl_4-Induced Liver Injury in Mice
- Development of Bioactive Functions in Hydrangeae Dulcis Folium. III. On the Antiallergic and Antimicrobial Principles of Hydrangeae Dulcis Folium. (1). thunberginols A, B, and F
- 3 消酒生薬成分の探索 : アルコール吸収抑制作用を示すサポニン類の構造と活性相関(口頭発表の部)
- 甘茶の機能開発(第2報)甘茶エキスの抗潰瘍活性, 抗アレルギー活性及び利胆活性
- ESCINS-Ia, Ib, IIa, IIb, AND IIIa, BIOACTIVE TRITERPENE OLIGOGLYCOSIDES FROM THE SEEDS OF AESCULUS HIPPOCASTANUM L. : THEIR INHIBITORY EFFECTS ON ETHANOL ABSORPTION AND HYPOGLYCEMIC ACTIVITY ON GLUCOSE TOLERANCE TEST
- ELATOSIDE E, A NEW HYPOGLYCEMIC PRINCIPLE FROM THE ROOT CORTEX OF ARALIA ELATA SEEM. : STRUCTURE-RELATED HYPOGLYCEMIC ACTIVITY OF OLEANOLIC ACID GLYCOSIDES
- Chemical Studies of Chinese Licorice-Roots. I. Elucidation of Five New Flavonoid Constituents from the Roots of Glycyrrhiza glabra L. Collected in Xinjiang
- 高速液体クロマトグラフィーによる甘茶Dihydroisocoumarin類の定量分析。加工調製の化学過程, 存在部位, 及び季節的変動の解析
- CAMELLIASAPONINS B_1,B_2,C_1 AND C_2,NEW TYPE INHIBITORS OF ETHANOL ABSORPTION IN RATS FROM THE SEEDS OF CAMELLIA JAPONICA L.
- ABSOLUTE STEREOSTRUCTURES OF PAEONISOTHUJONE, A NOVEL SKELETAL MONOTERPENE KETONE, AND DEOXYPAEONISUFFRONE, AND ISOPAEONISUFFRAL, TWO NEW MONOTERPENES, FROM MOUTAN CORTEX
- CHEMICAL TRANSFORMATION FROM DIHYDROISOCOUMARIN INTO BENZYLIDENEPHTHALIDE BY USE OF REGIOSPECIFIC OXIDATIVE LACTONIZATION MEDIATED BY COPPER CHLORIDE (II) : SYNTHESES OF THUNBERGINOL F AND HYDRAMACROPHYLLOL A AND B
- ベトナム産マンゴスチン(Garcinia mangostana L.)果皮の抗酸化活性成分
- インドネシア薬用植物 第VI報 : フローレス島で収集したPicrasma javanica(ニガキ科)樹皮の成分ピクラジャバニンA及びBの立体化学構造(発表論文抄録(1993))
- ELATOSIDES A AND B, POTENT INHIBITORS OF ETHANOL ABSORPTION IN RATS FROM THE BARK OF ARALIA ELATA SEEM : THE STRUCTURE-ACTIVITY RELATIONSHIPS OF OLEANOLIC ACID OLIGOGLYCOSIDES
- ABSOLUTE STEREOSTRUCTURES OF PAEONISUFFRONE AND PAEONISUFFRAL, TWO NEW LABILE MONOTERPENES, FROM CHINESE MOUTAN CORTEX
- 茶花の史的考察
- 茶樹及び茶花の史的考察--特に茶花の食品としての利用
- 特別講演 薬用食品に生体機能分子を探る (第1回食品薬学シンポジウム講演要旨集)
- 60(P-31) 薬用ハーブに抗肥満作用成分を探る : Salacia,Artichoke,Sage(ポスター発表の部)
- THUNBERGINOLS C, D, AND E, NEW ANTIALLERGIC AND ANTIMICROBIAL DIHYDROISOCOUMARINS, AND THUNBERGINOL G 3'-O-GLUCOSIDE AND (-)-HYDRANGENOL 4'-O-GLUCOSIDE, NEW DIHYDROISOCOUMARIN GLYCOSIDES, FROM HYDRANGEAE DULCIS FOLIUM
- Indonesian Medicinal Plants. VI. On the Chemical Constituents of the Bark of Picrasma javanica BL. (Simaroubaceae) from Flores Island. Absolute Stereostructures of Picrajavanins A and B
- Medicinal Foodstuffs. XXIV.^ Chemical Constituents of the Processed Leaves of Apocynum venetum L. : Absolute Stereostructures of Apocynosides I and II
- 82(P-39) 薫香生薬(没薬,乳香,木香)の一酸化窒素産生抑制テルペノイド成分(ポスター発表の部)
- Medicinal Foodstuffs.XXVII.^ Saponin Constituents of Gotu Kola(2) : Structures of New Ursane- and Oleanane-Type Triterpene Oligoglycosides, Centellasaponins B, C, and D, from Centella asiatica Cultivated in Sri Lanka
- 注目される機能性ハーブ (特集 高齢者におけるサプリメントの意義と問題点)
- 薬用食物にみる生理機能(46)大良姜と良姜
- 薬用食物にみる生理機能(45)茶花
- 薬用植物にみる整理機能(44)ニクジュヨウとカンカニクジユヨウ
- 薬用食物にみる生理機能(39)トウガラシとコショウ
- 薬用食物にみる生理機能(36)サンザシとセイヨウサンザシ
- 薬用食物にみる生理機能(35)ボダイジュ
- 薬用食物にみる生理機能(28)セージとローズマリー
- 薬用食物にみる生理機能(33)ニンニク
- 薬用食物にみる生理機能(32)アロエ
- 薬用食物にみる生理機能(27)エキナセアとノコギリヤシ
- 薬用食物にみる生理機能(25)アガリクスとキノコ由来の抗がん剤
- 薬用食物にみる生理機能(24)ニンジン
- 薬用食物にみる生理機能(23)ツボクサ
- 薬用食物にみる生理機能(21)サラシア
- 薬用食物にみる生理機能(20)三七人参
- 薬用食物にみる生理機能(19)梅
- 食用であり薬用である植物の薬理活性成分の探索 (今月の主題 漢方薬・生薬と臨床検査) -- (活性成分探索・解析)
- 115(P-66) 数種のファラオ天然薬物から得られた新奇化合物の構造と薬理活性(ポスター発表の部)
- Bioactive Constituents from Chinese Natural Medicines. XIV. New Glycosides of β-Carboline-Type Alkaloid, Neolignan, and Phenylpropanoid from Stellaria dichotoma L. var. lanceolata and Their Antiallergic Activities
- Medicinal Flowers. VI. : Absolute Stereostructures of Two New Flavanone Glycosides and a Phenylbutanoid Glycoside from the Flowers of Chrysanthemum indicum L. : Their Inhibitory Activities for Rat Lens Aldose Reductase
- J-2 川骨の一酸化窒素産生抑制および癌転移抑制作用成分
- Assessing the efficacy of famotidine and rebamipide in the treatment of gastric mucosal lesions in patients receiving long-term NSAID therapy (FORCE-famotidine or rebamipide in comparison by endoscopy)
- 巷の健康食品ブーム, 週刊誌やワイドショーにまかせてよいのか?
- Selective aldosterone blocker, eplerenone, attenuates hepatocellular carcinoma growth and angiogenesis in mice
- Branched-chain amino acids suppress insulin-resistance-based hepatocarcinogenesis in obese diabetic rats
- The role of radixin in altered localization of canalicular conjugate export pump Mrp2 in cholestatic rat liver
- Angiotensin-II and vascular endothelial growth factor interaction plays an important role in rat liver fibrosis development
- 第17回国際植物生長物質会議に参加して
- タバコ(Nicotiana tabacum)トライコームの重金属集積および排出機構に関する研究