Studies on Sulfur-containing Chelating Agents. VII. Syntheses of β-Mercaptothiolic Acid Esters and their Metal Chelates.
スポンサーリンク
概要
- 論文の詳細を見る
S-Esters of β-mercaptothiohydrocinnamic acid were prepared by the addition of hydrogen sulfide to the S-esters of thiocinnamic acid. S-Methyl, -ethyl, -isopropyl, -butyl, -isopentyl, -dodecyl, -phenyl, and-benzyl esters were prepared and their chelating ability with metals was tested. They formed stable chelates with copper and nickel, and the ratio of ligand to the metal was 1 : 1 in copper chelate and 2 : 1 in nickel, chelate. Cobalt chelate was stable only in the organic solvent, with the ratio of 3 : 1. S-Isopentyl β-mercaptothiohydrocinnamate was very sensitive with nickel and recognizable limit of nickel by this compound was 0.05γ/0.05 cc.
- 公益社団法人日本薬学会の論文
- 1962-01-25
著者
-
田中 久
Faculty of Pharmaceutical Sciences, Kyoto University
-
横山 陽
Faculty of Pharmaceutical Sciences, Kyoto University
-
横山 陽
Department Of Radiopharmaceutical Chemistry Faculty Of Pharmaceutical Sciences Kyoto University
関連論文
- Distribution of Some Disulfhydryl-Containing Chelating Agents labeled with Indium-113m and Gallium-67 in Mice
- Radioprotective Effect of Ergothioneine on γ-Irradiation of Metmyoglobin : Comparison with Cysteine on Sulfmyoglobin-Formation
- Metal Complexes of Ergothioneine
- Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N,N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide(Analytical,Chemical)
- Peroxidase-like Accelerative Activity of Ion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of Phenol with 4-Aminoantipyrine by Hydrogen Peroxide(Analytical,Chemical)
- Catalase-like Catalytic Activity of Ion-Exchange Resins Modified with Metalloporphyrins
- Dimethylsulfoxide Clathrates of Metal Complexes of β-Mercaptothiocinnamamide Derivatives
- Synthesis and Properties of Bis (N-methyl-, N-phenyl-β-mercaptothiocinnamamido) palladium (II)
- Synthesis and Properties of N-(2-Methylphenyl)- and N-(2,6-Dimethylphenyl)-β-mercaptothiocinnamamide and Their Palladium (II) Complexes
- A Novel Method of Preparation of Bis (dithiobenzoylacetonato) Zn (II)
- Synthesis and Properties of Bis (N-phenyl-β-mercaptothiocinnamamido) Ni (II)
- Synthesis and Properties of Bis (N-phenyl-β-mercapto-thiocinnamamido) Pd (II)
- Preparation of a New Dithioligand
- Studies on the Sulfur-containing Chelating Agents. XLVI. Hydrolysis of Thio-β-diketones and Related Amides in Acetonitrile-Water Mixture
- TcO4-イオンとヒト血清アルブミンの結合--アニオンとの拮抗〔英文〕
- Studies on the Sulfur-containing Chelating Agents. XLV. Kinetics of Ligand Exchange Reaction of Mercury-Monothiodibenzoylmethane Complex with Some Thiol Compounds by Stripping Solvent Extraction
- Studies on the Sulfur-containing Chelating Agents. XLIV. Kinetic Study of Ligand Exchange Reaction of Mercury-Aminopolycarboxylate with Monothiodibenzoylmethane by Solvent Extraction Method
- Studies on the Sulfur-containing Chelating Agents. XLIII. The Reaction of Thio-β-diketones and the Related Compounds with Iron (II) in the Presence of Pyridine
- Studies on the Sulfur-containing Chelating Agents. XLII. Solvent Extraction of Nickel (II) and Zinc (II) with N-(p-Substituted phenyl)-β-mercaptocinnamamides
- Studies on the Sulfur-containing Chelating Agents. XXXIX. Determination of Stability Constants of Some Metal Complexes of N-Phenyl-and N-Ethyl-β-mercaptocinnamamide and Thiodibenzoyl-methane by Solvent Extraction Method
- Studies on the Sulfur-containing Chelating Agents. XXXVIII. Reaction of Platinum (II), Rhodium (III) and Mercury (II) Ion with Monothio-β-diketones and Their Disulfides
- Studies on the Sulfur-containing Chelating Agents. XXXVII. Solvent Effect on Nuclear Magnetic Resonance Spectra of Cobalt (III) Monothioacetylacetonate and Its Brominated Products
- Noninvasive Measurement of Cerebral Blood Flow and Glucose Metabolic Rate in the Rat with High-Resolution Animal Positron Emission Tomography (PET) : A Novel in Vivo Approach for Assessing Drug Action in the Brains of Small Animals
- Radioiodinated N-(2-Aminoethyl)-2-chloro-4-iodobenzamide : A New Ligand for Monoamine Oxidase B Studies with Single Photon Emission Computed Tomography
- Differential Aging Pattern of Cerebral Accumulation of Radiolabeled Glucose and Amino Acid in the Senescence Accelerated Mouse (SAM), a New Model for the Study of Memory Impairment
- Synthesis and Characterization of ^C-Labeled Fluoroclorgyline : A Monoamine Oxidase A Specific Inhibitor for Positron Emission Tomography
- Synthesis and Evaluation of Iodinated Benzamide Derivatives as Selective and Reversible Monoamine Oxidase B Inhibitors
- Synthesis of (S)-N-[Methyl-^C]nicotine and Its Regional Distribution in the Mouse Brain : A Potential Tracer for Visualization of Brain Nicotinic Receptors by Positron Emission Tomography
- Synthesis of [^I]Iodoclorgyline, a Selective Monoamine Oxidase A Inhibitor, and Its Biodistribution in Mice
- Synthesis of Fluorine and Iodine Analogues of Clorgyline and Selective Inhibition of Monoamine Oxidase A
- Radioiodinated Phenoxyacetic Acid Derivatives as Potential Brain Imaging Agents. II. : Structure Biodistribution Relationship
- Redioiodinated Phenoxyacetic Acid Derivatives as Potential Brain Imaging Agents. I. : Effcient Synthesis via Trimethylsilyl Intermediates
- Ga-Labeling of Immunoglobulin G with High Specific Radioactivity
- Recirculatory Moment Analysis of Drugs in Man : Estimation of Extraction Ratio and Mean Cycle Time for Single Systemic and Pulmonary Circulation
- Cu-ATSM, an Intracellular-Accessible Superoxide Dismutase (SOD)-Like Copper Complex : Evaluation in an Ischemia-Reperfusion Injury Model
- Mitochondria-Selective Reduction of ^Cu-Pyruvaldehyde Bis(N^4-methylthiosemicarbazone) (^Cu-PTSM) in the Murine Brain; a Novel Radiopharmaceutical for Brain Positron Emission Tomography (PET) Imaging
- Development of Effective Cross-Linking Method for Bioactive Substance : Enzyme Immobilization Using Glutaraldehyde Oligomers
- Effect of Protein Binding on High Performance Liquid Chromatography Analysis of Drugs with an Internal-Surface Reversed-Phase Silica Column
- A Nonlinear Least Squares Program, MULTI(FILT), Based on Fast Inverse Laplace Transform for Microcomputers
- Electrokinetic Chromatography for Drug Analysis. Separation and Determination of Cefpiramide in Human Plasma
- Determination of Free Drug in Protein Binding Equilibrium by High-Performance Frontal Analysis Using Internal-Surface Reversed-Phase Silica Support
- Polymerization Reaction in Aqueous Solution of Glutaraldehyde Containing Trioxane-Type Oligomers under Sterilizing Conditins
- ANALYSIS OF WARFARIN-ALBUMIN BINDING BY HPLC WITH INTERNAL-SURFACE REVERSED-PHASE SILICA COLUMN
- SEPARATION AND DETERMINATION OF CEFPIRANIDE IN HUMAN PLASMA BY ELECTROKINETIC CHROMATOGRAPHY WITH A MICELLAR SOLUTION AND AN OPEN TUBULAR-FUSED SILICA CAPILLARY
- Isolation and Identification of New Oligomers in Aqueous Solution of Glutaraldehyde(Analytical,Chemical)
- Effect of Probenecid on Disposition of Cefpiramide in Rat. : The Application of Population Pharmacokinetics(Pharmaceutical)
- Automated System of Dissolution Testing with Data Input through RS-232C Interface of a Personal Computer
- Application of [^I] (S)-5-Iodonicotine, a New Radioiodinated Ligand, in the Assay of Nicotinic Acetylcholine Receptor Binding in the Brain
- An Approach for Assaying Benzodiazepine Receptor Binding with Radioiodinated Ligand : ^I-Labeled Diazepam Derivative
- Evaluation of N-Alkyl Derivatives of Radioiodinated Spiperone as Radioligands for in Vivo Dopamine D_2 Receptor Studies : Effects of Lipophilicity and Receptor Affinity on the in Vivo Biodistribution
- A Synthetic Method Suitable for the Rapid Preparation of ^N-Labeled Dermorphin Analogue, H-Try-D-Met(O)-Phe-Gly-NH_2 (SD-62)
- Polynuclear and Mononuclear Complex Formation between Indium (III) and Sulfhydryl-containing Bidentate Ligands
- Solution Equilibria and Structures of Disulfhydryl-containing Peptide-Indium (III) and Gallium (III) Complex Species
- Hydroxylation of Acetanilide by Iron-Sulfur and Nickel-Sulfur Complex Systems
- Interaction of Albumin, Transferrin, and Human Serum with Indium-113 m Complexes of Ethylenediaminetetraacetic Acid, Penicillamine, and Related Compounds
- Proton Magnetic Resonance Study of Indium (III) and Gallium (III) Binding by Adjacent and Separated Disulfhydryl-Containing Peptides
- Spectroscopic and Catalytic Properties of Penicillamine-Molybdenum Complexes
- Effect of Inorganic Sulfur and Selenium on O_2-Uptake and Aniline Hydroxylation by Dithiothreitol-Iron Complex in Comparison with Adrenodoxin and Se-Adrenodoxin
- Studies on the Sulfur-containing Chelating Agents. XXXIII. Interaction of Penicillamine and Its Related Compounds with Chromium Ion and Hemoglobin-bound Chromium
- Studies on the Sulfur-containing Chelating Agents. XXVI. Formation of Mixed Ligand Chelates Containing Penicillamine and Sulfhydryl Compounds
- Studies on Imidazole Derivatives as Chelating Agents. III. Syntheses of Schiff Bases and 4 (5)-Aminomethyl Derivatives and Their Reactions with Metal Ions.
- Studies on Imidazole Derivatives as Chelating Agents. II. Spectrophotometric and Potentiometric Investigations of Acid-base Equilibria of Azoimidazoles
- Studies on Imidazole Derivatives as Chelating Agents. I. Syntheses of Azoimidazoles and Their Reactions with Metal Ions
- Imidazolylazo Compounds as Metallochromic Indicators
- Investigation of Radiopharmaceuticals for Pancreatic Imaging : Accumulation of Amines in the Pancreas
- Cu-Pyruvaldehyde-bis (N^4-methylthiosemicarbazone) (Cu-PTSM), a Metal Complex with Selective NADH-Dependent Reduction by Complex I in Brain Mitochondria : A Potential Radiopharmaceutical for Mitochondria-Functional Imaging with Positron Emission Tomograph
- Studies on the Sulfur-containing Chelating Agents. XXIV. Acid Dissociation and Chelate Formation of Penicillamine
- Studies on the Sulfur-containing Chelating Agents. XXV. Chelate Formation of Penicillamine and Its Related Compounds with Copper (II)
- Reduction of Selenocystamine by Thiols
- Studies on the Sulfur-containing Chelating Agents. XXXI. Catalytic Effect of Copper (II) Ion to Formation of Mixed Disulfide
- Syntheses of Metal Complexes of Selenocysteamine
- Syntheses of Related Compounds of Selenocysteamine and Their Complex Formation with Metal Ions
- Studies on the Sulfur-containing Chelating Agents. XXIX. Reaction of Cysteamine and Its Related Compounds with Copper
- Metal Complexes of Selenocysteamine
- Acid Dissociation of Selenocysteamine (2-Aminoethaneselenol)
- Studies on the Sulfur-containing Chelating Agents. XXXVI. Reaction of Palladium Monothioacetylacetonate with Sulfide Ion and Its Application for Determination of Sulfide Ion
- Studies on the Sulfur-containing Chelating Agents. XXXII. The Reaction of Palladium (II) Ion with Monothio-β-diketones and Their Disulfides
- Studies on the Sulfur-containing Chelating Agents. XXIII. Some Investigations on the Quasiaromaticity of Cobalt (III) Thio-β-diketonates by the Spectroscopic Methods
- Studies on the Sulfur-containing Chelating Agents. XXII. Some Metal Chelates of Thio-β-diketones and Bromination of Cobalt (III) Thio-β-diketonates
- The Metal Chelates of Thio Derivatives of β-Diketones
- The Effect of the Alkaline Earth Salts on the NMR Spectrum of Phenols
- Syntheses and Chelating Properties of Azothiopyrine Sulfonates
- Studies on the Sulfur-containing Chelating Agents. XIV. Syntheses of β-Mercaptocinnamamides and their Structures.
- Studies on the Sulfur-containing Chelating Agents. XXXIV. Determination of Stability Constant of Mercury Complex of Monothiodibenzoylmethane and Monothiothenoyltrifluoroacetone by Solvent Extraction Method
- Studies on the Sulfur-containing Chelating Agents. XXXV. Determination of Acid Dissociation Constants of N-Phenyl- and N-Ethyl-β-mercaptocin-namamide and Thiodibenzoylmethane by Solvent Extraction Method
- Studies on the Sulfur-containing Chelating Agents.XV.Thioxo-thioenol Tautomerism in Ethyl β-Mercaptothiocinnamates and β-Mercaptocinnamamides
- Studies on the Sulfurcontaining Chelating Agents. XIII. Syntheses of Esters of β-Mercaptothiocinnamic Acid and their Structures.
- Studies on the Sulfurcontaining Chelating Agents. XII. Relationship between Chelating Ability and Chemical Structure of Ligand. (2).
- Studies on the Sulfurcontaining Chelating Agents. XI. Relationship between Chelating Ability and Chemical Structure of Ligand. (1).
- Studies on Sulfur-containing Chelating Agents. X. Mercapto-acid Amides and their Metal Chelates.
- Studies on Sulfur-containing Chelating Agents. IX. Syntheses of Alkyl or Aryl o-Mercaptophenyl Ketones, Esters of o-Mercaptobenzoic Acid, S-Esters of o-Mercaptothiobenzoic Acid, and their Metal Chelates.
- Studies on Sulfur-containing Chelating Agents. VIII. Syntheses of α, β-Unsaturated β-Mercapto-acid Esters and their Metal Chelates.
- Studies on Sulfur-containing Chelating Agents. VII. Syntheses of β-Mercaptothiolic Acid Esters and their Metal Chelates.
- Studies on the Sulfur-containing Chelating Agents. VI. Syntheses of β-Mercapto-acid Esters and their Copper and Nickel Chelates.
- Studies on the Sulfur-containing Chelating Agents. V. : Syntheses of β-Mercapto-acid Esters, and their Copper and Nickel Chelates. (1).
- Studies on the Sulfur-containing Chelating Agents. IV. : Structure of Copper Chelate of β-Mercaptoketones.
- Studies on the Sulfur-containing Chelating Agents. III. : Syntheses of β-Mercaptoketones and their Copper Chelates. (3)
- Studies on the Sulfur-containing Chelating Agents. II. Syntheses of β-Mercaptoketones and their Copper Chelates. (2).
- Studies on the sulfur-containing Chelating Agents. I.. Syntheses of β-Mercaptoketones and their Copper Chelates. (1)