Studies on the sulfur-containing Chelating Agents. I.. Syntheses of β-Mercaptoketones and their Copper Chelates. (1)
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概要
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β-Mercaptoketones were prepared as a new type of chelating agent in which the mercapto and keto groups take part in chelate formation. β-Mercapto-β-phenylpropio-phenone was prepared by the addition of hydrogen sulfide to α-benzylideneacetophenone under pressure. This method was applied to the syntheses of β-mercapto-β-(p-methoxyphenyl)-, α-methyl-β-mercapto-β-phenyl-, and α, β-diphenyl-β-mercaptopropiophenones. In most cases, corresponding disulfides were also obtained as a result of the addition of hydrogen sulfide. These mercaptoketones formed orange-yellow chelates with copper and the ratio of ligand to copper was found to be 1 : 1.
- 公益社団法人日本薬学会の論文
- 1960-04-25
著者
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田中 久
Faculty of Pharmaceutical Sciences, Kyoto University
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横山 陽
Faculty of Pharmaceutical Sciences, Kyoto University
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横山 陽
Department Of Radiopharmaceutical Chemistry Faculty Of Pharmaceutical Sciences Kyoto University
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- Studies on the sulfur-containing Chelating Agents. I.. Syntheses of β-Mercaptoketones and their Copper Chelates. (1)