Studies on the Sulfur-containing Chelating Agents. XXXIII. Interaction of Penicillamine and Its Related Compounds with Chromium Ion and Hemoglobin-bound Chromium
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概要
- 論文の詳細を見る
The chelating agents containing sulfhydryl group, such as penicillamine and cysteine, formed stable chromium (III) complexes by the reductive chelate formation with sodium chromate. The sulfur-containing ligands coordinated with chromium (III) ion through their sulfur atom, and the nephelauxetic effect in chromium (III) complexes occured to a larger extent with sulfur-containing ligands than the other ligands. The effects of the chelating agents containing sulfhydryl group on the removal of chromium bound to hemoglobin were compared with those of ascorbic acid and EDTA, and the sulfur-containing ligands were superior to ascorbic acid and EDTA, in the rate and the amount of the removal of chromium.
- 社団法人日本薬学会の論文
- 1972-07-25
著者
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田中 久
Faculty of Pharmaceutical Sciences, Kyoto University
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杉浦 幸雄
Faculty of Pharmaceutical Sciences, Kyoto University
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杉浦 幸雄
京大薬
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北條 康司
Faculty Of Pharmaceutical Sciences Kyoto University
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杉浦 幸雄
Faculty Of Pharmaceutical Sciences Kyoto University
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