Polymerization Reaction in Aqueous Solution of Glutaraldehyde Containing Trioxane-Type Oligomers under Sterilizing Conditins
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概要
- 論文の詳細を見る
The precipitate, deposited in a 2% alkaline aqueous solution (pH 7.5-8.5) of glutaraldehyde (GA) used for chemosterilization of medical instruments, was characterized by means of thermogravimetry, pyrolysis gas chromatography, chemical ionization mass spectrometry and high-performance liquid chromatography. It was found that the precipitation could be attributed to the polymerization reaction based on aldol condensation involving both GA monomer and trioxane-type GA oligomers. The polymers produced had an average molecular weight higher than those obtained from GA alone. The relation between the turbidity of GA solution and the molecular of the polymer indicated that the precipitates included polymer with a molecular weight exceedings approximately 12000.
- 社団法人日本薬学会の論文
- 1989-02-25
著者
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田中 久
Faculty of Pharmaceutical Sciences, Kyoto University
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田中 久
Kyoto Pharmaceutical University
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中川 照眞
Faculty Of Pharmaceutical Sciences Kyoto University
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中川 照眞
京都大学 薬研究
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中川 照真
京都大学薬学部
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中川 照眞
京都大学薬学部
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中川 照眞
京大 大学院薬学研究科
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田嶋 敏男
Central Research Laboratory Maruishi Pharmaceutical Co. Ltd.
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原田 みち子
Central Research Laboratory Maruishi Pharmaceutical Co. Ltd.
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今井 雅裕
Central Research Laboratory, Maruishi Pharmaceutical Co., Ltd.,
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川上 宇良雄
Central Research Laboratory, Maruishi Pharmaceutical Co., Ltd.,
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佐藤 信勝
Central Research Laboratory, Maruishi Pharmaceutical Co., Ltd.,
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今井 雅裕
Central Research Laboratory Maruishi Pharmaceutical Co. Ltd.
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佐藤 信勝
Central Research Laboratory Maruishi Pharmaceutical Co. Ltd.
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川上 宇良雄
Central Research Laboratory Maruishi Pharmaceutical Co. Ltd.
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