Preparation of a New Dithioligand
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概要
- 論文の詳細を見る
A new dithio ligand containing sulfhydryl and thioamido group, N-phenyl-β-mercapto-thiocinnamamide, was prepared and its properties were studied. Although the nuclear magnetic resonance (NMR) spectrum did not show the SH signal, the v(SH) was observed in the infrared (IR) spectrum. The mass spectrum and the molecular weight estimation revealed that the ligand has a monomer structure. The λ_<max> (ε) in EtOH are as follows ; 347 nm (15600), 265 and 229 sh. The pK_a value in 10% EtOH aqueous solution was determined spectrophotometrically to be 3.16±0.03. The low pK_a value was supposed to be an existence of a strong hydrogen bond.
- 社団法人日本薬学会の論文
- 1978-04-25
著者
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田中 久
Faculty of Pharmaceutical Sciences, Kyoto University
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北川 進
Faculty of Pharmaceutical Sciences, Kyoto University
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北川 進
Faculty Of Pharmaceutical Sciences Kyoto University
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