SEPARATION AND DETERMINATION OF CEFPIRANIDE IN HUMAN PLASMA BY ELECTROKINETIC CHROMATOGRAPHY WITH A MICELLAR SOLUTION AND AN OPEN TUBULAR-FUSED SILICA CAPILLARY
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概要
- 論文の詳細を見る
Electrokinetic chromatography was used to determine cefpiramide (CPM) in human plasma, using antipyrine (AP) as an internal standard. A plasma sample was introduced into a fused silica capillary. Then high voltage was applied between the ends of the capillary dipped in a phosphate buffer solution containing sodium dodecyl sulfate above critical micellar concentration (CMC). The CPM and AP were separeted from each other and from plasma proteins within 5 min. The calibration line indicated good linearity in the concentration range over 10 to 300 μg/ml.
- 社団法人日本薬学会の論文
- 1988-04-25
著者
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田中 久
Faculty of Pharmaceutical Sciences, Kyoto University
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田中 久
Kyoto Pharmaceutical University
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小田 吉哉
Faculty Of Pharmaceutical Sciences Kyoto University
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中川 照眞
Faculty Of Pharmaceutical Sciences Kyoto University
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中川 照眞
京都大学 薬研究
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中川 照真
京都大学薬学部
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中川 照眞
京都大学薬学部
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中川 照眞
京大 大学院薬学研究科
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渋川 明正
Faculty of Pharmaceutical Sciences, Kyoto University
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渋川 明正
京大 大学院薬学研究科
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