Distribution of Some Disulfhydryl-Containing Chelating Agents labeled with Indium-113m and Gallium-67 in Mice
スポンサーリンク
概要
- 論文の詳細を見る
The organ distribution of new disulfhydryl-compounds, 2,3-dimercaptopropionyl-glycine (DMPG) and 2-mercaptopropionyl-L-cysteine (MPC), labeled with ^<113m>In (III) and ^<67>Ga (III) were examined in mice, and the results were compared with those of dimercaptosuccinic acid complex and metal ion without those ligands to evaluate their applicabilities as diagnostic agent in nuclear medicine. The DMPG complex was found to be localized in liver, whereas the MPC complex in kidney. The addition of metal ion carrier varies the distribution patterns of the complex species, on account of the formation of the polymerized products. In the case of indium complexes, the behavior of the ligand was reflected to their distribution patterns more clearly than in the case of gallium complexes. The complex species formed in the labeling reactions were characterized by the electrophoretic and gel-filtration techniques.
- 社団法人日本薬学会の論文
- 1979-02-25
著者
-
森 五彦
Kobe Women's College of Pharmacy
-
森 五彦
Department Of Radiopharmaceutical Chemistry Kobe Women's College Of Pharmacy
-
森 五彦
神戸薬科大
-
田中 久
Faculty of Pharmaceutical Sciences, Kyoto University
-
本橋 範子
Department Of Radiopharmaceutical Chemistry Kobe Women's College Of Pharmacy
-
本橋 範子
神戸薬科大学
-
杉浦 幸雄
京大薬
関連論文
- 脾臓の免疫機能イメ-ジング剤としてのプトレシンの有用性〔英文〕
- 腫瘍細胞移植によるマウス脾臓中のポリアミン含量及びその代謝関連酵素活性について
- In VitroおよびIn Vivoにおけるラット肝臓メタロチオネインとカドミウム, 銅, 亜鉛の結合について
- ラット肝臓中のメタロチオネイン生成における誘導金属量について
- The Concentrations of the Bound Metals in Hepatic Metallothionein of Rats injected with Cadmium
- 中性子放射化分析による生体中微量元素の研究(第4報)正常ラットおよびカドミウム投与ラット肝臓可溶性蛋白の結合金属元素について
- The Study of Elements in Organisms by Neutron Activation Analysis. III. The Distribution of Trace Elements in Various Organs of Normal Rat and in Cell Fractions of Rat Liver
- 中性子放射化分析による大麻葉の多種類元素分析 : 国内産大麻の産地別比較
- 中性子放射化分析による生体中微量元素の研究(第2報)栽培大麻の各部位における無機元素の分布について
- 中性子放射化分析法による大麻中のリンの定量-^Pの液体シンチレーションスペクトロメーターによるチェレンコフ光測定-
- Isolation and Characterization of α-Mercaptopropionylglycine-2,4-Dihydroxyphenylalanine Conjugates Produced through Mushroom Tyrosinase Reaction
- Inhibitory Effects of Sulfur Compounds on Melanin Formation Reaction by Tyrosinase
- Concentration and Degradation of Hyaluronic Acid in Knee Synovial Fluid from Carrageenin-Induced Rabbit Arthritis
- Quantitation of Hyaluronic Acid and Chondroitin Sulphates in Rabbit Synovial Fluid by High-Performance Liquid Chromatography of Oligosaccharides Enzymatically Derived Thereof
- The Role of Ergothioneine in the Oxidation of Reduced Nicotinamide Adenine Dinucleotide by Metmyoglobin or Methemoglobin
- Radioassay for Oxidation of Tyrosine by Tyrosinase using L-[Ring-^3H] tyrosine and L-[Carboxyl-^C] tyrosine
- L-リジンおよびポリ-L-リジンの57Coによる標識反応とそれらの正常およびエ-ルリッヒ担がんマウスにおける体内分布
- Distribution of Some Disulfhydryl-Containing Chelating Agents labeled with Indium-113m and Gallium-67 in Mice
- Radioprotective Effect of Ergothioneine on γ-Irradiation of Metmyoglobin : Comparison with Cysteine on Sulfmyoglobin-Formation
- RI取扱者としての基礎知識は充分条件でない(薬学におけるFIの教育と研究の課題)
- Complexing of Copper Ion by Ergothioneine
- ^13C-Nuclear Magnetic Resonance and Raman Spectroscopic Studies on Ionization and Mercury Complex of Ergothioneine
- Metal Complexes of Ergothioneine
- Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N,N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide(Analytical,Chemical)
- Peroxidase-like Accelerative Activity of Ion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of Phenol with 4-Aminoantipyrine by Hydrogen Peroxide(Analytical,Chemical)
- Catalase-like Catalytic Activity of Ion-Exchange Resins Modified with Metalloporphyrins
- Dimethylsulfoxide Clathrates of Metal Complexes of β-Mercaptothiocinnamamide Derivatives
- Synthesis and Properties of Bis (N-methyl-, N-phenyl-β-mercaptothiocinnamamido) palladium (II)
- Synthesis and Properties of N-(2-Methylphenyl)- and N-(2,6-Dimethylphenyl)-β-mercaptothiocinnamamide and Their Palladium (II) Complexes
- A Novel Method of Preparation of Bis (dithiobenzoylacetonato) Zn (II)
- Synthesis and Properties of Bis (N-phenyl-β-mercaptothiocinnamamido) Ni (II)
- Synthesis and Properties of Bis (N-phenyl-β-mercapto-thiocinnamamido) Pd (II)
- Preparation of a New Dithioligand
- Studies on the Sulfur-containing Chelating Agents. XLVI. Hydrolysis of Thio-β-diketones and Related Amides in Acetonitrile-Water Mixture
- Studies on the Sulfur-containing Chelating Agents. XLV. Kinetics of Ligand Exchange Reaction of Mercury-Monothiodibenzoylmethane Complex with Some Thiol Compounds by Stripping Solvent Extraction
- Studies on the Sulfur-containing Chelating Agents. XLIV. Kinetic Study of Ligand Exchange Reaction of Mercury-Aminopolycarboxylate with Monothiodibenzoylmethane by Solvent Extraction Method
- Studies on the Sulfur-containing Chelating Agents. XLIII. The Reaction of Thio-β-diketones and the Related Compounds with Iron (II) in the Presence of Pyridine
- Studies on the Sulfur-containing Chelating Agents. XLII. Solvent Extraction of Nickel (II) and Zinc (II) with N-(p-Substituted phenyl)-β-mercaptocinnamamides
- Studies on the Sulfur-containing Chelating Agents. XXXIX. Determination of Stability Constants of Some Metal Complexes of N-Phenyl-and N-Ethyl-β-mercaptocinnamamide and Thiodibenzoyl-methane by Solvent Extraction Method
- Studies on the Sulfur-containing Chelating Agents. XXXVIII. Reaction of Platinum (II), Rhodium (III) and Mercury (II) Ion with Monothio-β-diketones and Their Disulfides
- Studies on the Sulfur-containing Chelating Agents. XXXVII. Solvent Effect on Nuclear Magnetic Resonance Spectra of Cobalt (III) Monothioacetylacetonate and Its Brominated Products
- 82. 我教室の精製Gonadotropinと米国NIH並びにKoln大学のGonadotropinとの電気泳動学的比較検討について
- 16. 豚下垂体前葉よりのGonadotropin並びに尿中Gonadotropinの連続濾紙電気永動法による分離と糖成分について
- Recirculatory Moment Analysis of Drugs in Man : Estimation of Extraction Ratio and Mean Cycle Time for Single Systemic and Pulmonary Circulation
- Development of Effective Cross-Linking Method for Bioactive Substance : Enzyme Immobilization Using Glutaraldehyde Oligomers
- Effect of Protein Binding on High Performance Liquid Chromatography Analysis of Drugs with an Internal-Surface Reversed-Phase Silica Column
- A Nonlinear Least Squares Program, MULTI(FILT), Based on Fast Inverse Laplace Transform for Microcomputers
- Electrokinetic Chromatography for Drug Analysis. Separation and Determination of Cefpiramide in Human Plasma
- Determination of Free Drug in Protein Binding Equilibrium by High-Performance Frontal Analysis Using Internal-Surface Reversed-Phase Silica Support
- Polymerization Reaction in Aqueous Solution of Glutaraldehyde Containing Trioxane-Type Oligomers under Sterilizing Conditins
- ANALYSIS OF WARFARIN-ALBUMIN BINDING BY HPLC WITH INTERNAL-SURFACE REVERSED-PHASE SILICA COLUMN
- SEPARATION AND DETERMINATION OF CEFPIRANIDE IN HUMAN PLASMA BY ELECTROKINETIC CHROMATOGRAPHY WITH A MICELLAR SOLUTION AND AN OPEN TUBULAR-FUSED SILICA CAPILLARY
- Isolation and Identification of New Oligomers in Aqueous Solution of Glutaraldehyde(Analytical,Chemical)
- Effect of Probenecid on Disposition of Cefpiramide in Rat. : The Application of Population Pharmacokinetics(Pharmaceutical)
- Automated System of Dissolution Testing with Data Input through RS-232C Interface of a Personal Computer
- 薬学と放射性医薬品
- Polynuclear and Mononuclear Complex Formation between Indium (III) and Sulfhydryl-containing Bidentate Ligands
- Solution Equilibria and Structures of Disulfhydryl-containing Peptide-Indium (III) and Gallium (III) Complex Species
- Hydroxylation of Acetanilide by Iron-Sulfur and Nickel-Sulfur Complex Systems
- Interaction of Albumin, Transferrin, and Human Serum with Indium-113 m Complexes of Ethylenediaminetetraacetic Acid, Penicillamine, and Related Compounds
- Proton Magnetic Resonance Study of Indium (III) and Gallium (III) Binding by Adjacent and Separated Disulfhydryl-Containing Peptides
- Spectroscopic and Catalytic Properties of Penicillamine-Molybdenum Complexes
- Effect of Inorganic Sulfur and Selenium on O_2-Uptake and Aniline Hydroxylation by Dithiothreitol-Iron Complex in Comparison with Adrenodoxin and Se-Adrenodoxin
- Studies on the Sulfur-containing Chelating Agents. XXXIII. Interaction of Penicillamine and Its Related Compounds with Chromium Ion and Hemoglobin-bound Chromium
- Studies on the Sulfur-containing Chelating Agents. XXVI. Formation of Mixed Ligand Chelates Containing Penicillamine and Sulfhydryl Compounds
- Studies on Imidazole Derivatives as Chelating Agents. III. Syntheses of Schiff Bases and 4 (5)-Aminomethyl Derivatives and Their Reactions with Metal Ions.
- Studies on Imidazole Derivatives as Chelating Agents. II. Spectrophotometric and Potentiometric Investigations of Acid-base Equilibria of Azoimidazoles
- Studies on Imidazole Derivatives as Chelating Agents. I. Syntheses of Azoimidazoles and Their Reactions with Metal Ions
- Imidazolylazo Compounds as Metallochromic Indicators
- Studies on the Sulfur-containing Chelating Agents. XXIV. Acid Dissociation and Chelate Formation of Penicillamine
- Studies on the Sulfur-containing Chelating Agents. XXV. Chelate Formation of Penicillamine and Its Related Compounds with Copper (II)
- Reduction of Selenocystamine by Thiols
- Studies on the Sulfur-containing Chelating Agents. XXXI. Catalytic Effect of Copper (II) Ion to Formation of Mixed Disulfide
- Syntheses of Metal Complexes of Selenocysteamine
- Syntheses of Related Compounds of Selenocysteamine and Their Complex Formation with Metal Ions
- Studies on the Sulfur-containing Chelating Agents. XXIX. Reaction of Cysteamine and Its Related Compounds with Copper
- Metal Complexes of Selenocysteamine
- Acid Dissociation of Selenocysteamine (2-Aminoethaneselenol)
- Studies on the Sulfur-containing Chelating Agents. XXXVI. Reaction of Palladium Monothioacetylacetonate with Sulfide Ion and Its Application for Determination of Sulfide Ion
- Studies on the Sulfur-containing Chelating Agents. XXXII. The Reaction of Palladium (II) Ion with Monothio-β-diketones and Their Disulfides
- Studies on the Sulfur-containing Chelating Agents. XXIII. Some Investigations on the Quasiaromaticity of Cobalt (III) Thio-β-diketonates by the Spectroscopic Methods
- Studies on the Sulfur-containing Chelating Agents. XXII. Some Metal Chelates of Thio-β-diketones and Bromination of Cobalt (III) Thio-β-diketonates
- The Metal Chelates of Thio Derivatives of β-Diketones
- Syntheses and Chelating Properties of Azothiopyrine Sulfonates
- Studies on the Sulfur-containing Chelating Agents. XIV. Syntheses of β-Mercaptocinnamamides and their Structures.
- Studies on the Sulfur-containing Chelating Agents. XXXIV. Determination of Stability Constant of Mercury Complex of Monothiodibenzoylmethane and Monothiothenoyltrifluoroacetone by Solvent Extraction Method
- 有害性重金属水銀(II),銅(II),鉛(II),カドミウム(II),ビスマス(III)の電気泳動による迅速分離ならびに定量 : 多そう式電気泳動法による研究(第3報)
- pHこう配利用による指示薬試薬の焦点ゾーン電気泳動法 : 多そう式電気泳動法による研究(第2報)
- Studies on the Sulfur-containing Chelating Agents. XXXV. Determination of Acid Dissociation Constants of N-Phenyl- and N-Ethyl-β-mercaptocin-namamide and Thiodibenzoylmethane by Solvent Extraction Method
- 7 電気泳動法
- 薄層クロマトシート電気泳動法による90Sr-90Y,212Pb-212Biの迅速分離
- Studies on the Sulfur-containing Chelating Agents.XV.Thioxo-thioenol Tautomerism in Ethyl β-Mercaptothiocinnamates and β-Mercaptocinnamamides
- Studies on the Sulfurcontaining Chelating Agents. XIII. Syntheses of Esters of β-Mercaptothiocinnamic Acid and their Structures.
- Studies on the Sulfurcontaining Chelating Agents. XII. Relationship between Chelating Ability and Chemical Structure of Ligand. (2).
- Studies on the Sulfurcontaining Chelating Agents. XI. Relationship between Chelating Ability and Chemical Structure of Ligand. (1).
- Studies on Sulfur-containing Chelating Agents. X. Mercapto-acid Amides and their Metal Chelates.
- Studies on Sulfur-containing Chelating Agents. IX. Syntheses of Alkyl or Aryl o-Mercaptophenyl Ketones, Esters of o-Mercaptobenzoic Acid, S-Esters of o-Mercaptothiobenzoic Acid, and their Metal Chelates.
- ペーパークロマトグラフィーによる上昇展開中のアルカリ金属イオンに対する電示的定量
- ペーパークロマトグラフィーにおける展開中の無機イオンに対する直流加電圧検出装置の試作