Synthesis of Glyceroyl β-N-Acetyllactosaminide and Its Derivatives through a Condensation Reaction by Cellulase(Biochemistry & Molecular Biology)
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概要
- 論文の詳細を見る
A condensation reaction between N-acetyllactosamine and glycerol was directly catalyzed by using a commercially available cellulase preparation from Trichoderma reesei. 1-O-β-N-Acetyllactosaminyl- (R, S) -glycerols (1) were readily synthesized in a 5% yield based on the N-acetyllactosamine added and conveniently isolated by two-step column chromatographies. The use of a partially purified enzyme increased 2.3-fold the yield of 1, compared to that of the crude enzyme containing β-D-galactosidase activity. When various alkanols (n : 2-4) were used in the condensation reaction, the corresponding alkyl β-N-acetyllactosaminides were obtained in yields of 0.3-1.1% of the desired compounds.
- 社団法人日本農芸化学会の論文
- 2003-07-23
著者
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村田 健臣
静岡大学創造科学技術大学院
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Usui T
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Usui Taichi
Department Of Agricultural Chemistry Faculty Of Agriculture Shizuoka University
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村田 健吾
静岡大学創造科学技術大学院
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Murata Takeomi
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Murata Takeomi
Department Of Applied Biological Cemistry Faculty Of Agriculture Shizuoka University
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Murata Takeomi
Department Of Biological Chemistry Faculty Of Agriculture Shizuoka University
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Usui Takeo
Department Of Biotechnology Faculty Of Agriculture And Life Science University Of Tokyo
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HARADA Yoichiro
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
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TOTANI Kazuhide
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
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YASUTAKE Nozomu
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
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YASUTAKE Nozomu
Science of Biological Resource, The United Graduate School of Agricultural Science, Gifu University
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HARAGUCHI Shinobu
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
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Usui T
Dep. Of Applied Biological Chemistry Fac. Of Agriculture Shizuoka Univ.
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Harada Y
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Kazuhide Totani
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Yasutake Nozomu
Science Of Biological Resource The United Graduate School Of Agricultural Science Gifu University
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Haraguchi Shinobu
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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TOTANI Kazuhide
Department of Agricultural Chemistry, Faculty of Agriculture, Shizuoka University
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