Purification and Characterization of Two Lectins from a Toxic Moray, Gymnothrax javanicus

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概要

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• Two lectins, Gymnothrax javanicus lectin-I (GJL-I) and Gymnothrax javanicus lectin-II (GJL-II) were isolated from the stomach and intestine, and the liver, respectively, of a toxic moray eel, Gymnothrax javanicus,. GJL-I is a polymer of two heterogeneous subunits of 67 and 51 kDa. In a hemagglutination inhibition assay, it had sugar-binding specificity toward lactose and lactulose among the mono- or oligo-saccharides and bovine submaxillary mucin (BSM) among the glycoproteins tested. The lectin stimulated nerve growth factor (NGF) synthesis by astroglial cells. GJL-II was a polymer of subunit of 41 kDa. This lectin had N-acetyllactosamine binding specificity.

• 社団法人日本農芸化学会の論文
• 2001-11-23

著者

• Kawagishi Hirokazu

  Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University

• Usui Taichi

  Department Of Agricultural Chemistry Faculty Of Agriculture Shizuoka University

• Murata Takeomi

  Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University

• Murata Takeomi

  Department Of Applied Biological Cemistry Faculty Of Agriculture Shizuoka University

• Murata Takeomi

  Department Of Biological Chemistry Faculty Of Agriculture Shizuoka University

• Kawagishi Hirokazu

  Graduate School Of Sci. And Technol. Shizuoka Univ.

• Furukawa Shoei

  Department Of Molecular Biology Gifu Pharmaceutical University

• YASUI Masaaki

  Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

• UNO Akinori

  Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

• FURUKAWA Syoei

  Department of Molecular Biology, Gifu Pharmaceutical University

• Usui Taichi

  Department Of Bioscience Graduate School Of Science And Technology Shizuoka University

• Kawagishi Hirokazu

  Department Of Applied Biochemistry Faculty Of Agriculture Shizuoka University

• KAWAGISHI Hirokazu

  Department of Agricultural Chemistry, Faculty of Agriculture

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