Effects of Okadaic Acid on Embryonic Development of the Starfish Asterina pectinifera

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概要

• 論文の詳細を見る

• The effects of okadaic acid, an inhibitor of protein phosphatases types 1 and 2A, from the sponge Halichondria okadai Kadota, on the embryonic development of the starfish Asterina pectinifera, were investigated. When cultured in okadaic acid from fertilization, the embryo divided synchronously without any abnormalities such as lysis, swelling or morphological changes different from control embryos up to the 32-cell stage. However, okadaic acid prevented development before the onset of blastulation. Cytological examination showed that chromosomes condensed but did not align in a plane in the mitotic apparatus in each of the blastomeres of the treated embryo at the sixth cleavage, suggesting that this was the root cause of the arrest of further development.

• 社団法人日本農芸化学会の論文
• 1992-07-23

著者

• Kajiyama Noboru

  Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine

• Kajiyama Noboru

  Department Of Applied Biochemistry Faculty Of Applied Biological Sciences Hiroshima University

• Shimizu Takahiko

  Department of Molecular Gerontology, Tokyo Metropolitan Institute of Gerontology

• KASAHARA Toshihiko

  Department of Molecular Toxicology and COE Program in the 21st Century, School of Pharmaceutical Sci

• Shimizu Takahiko

  Department Of Applied Biochemistry Faculty Of Applied Biological Sciences Hiroshima University

• SHIODA Masaki

  Department of Biological Science, Faculty of Science, Kumamoto University

• Shimizu Toshio

  Foods Research Group, Foods Division, Asahi Chemical Industry Co., Ltd.

• IKEGAMI Susumu

  Department of Applied Biochemistry, Faculty of Applied Biological Sciences, Hiroshima University

• UEMURA Daisuke

  Faculty of Liberal Arts, Shizuoka University

• OZAKI Yoshihiro

  Department of Applied Biochemistry, Hiroshima University

• OOE Yasunori

  Department of Applied Biochemistry, Hiroshima University

• Ooe Yasunori

  Department Of Applied Biochemistry Hiroshima University

• Uemura Daisuke

  Faculty Of Liberal Arts Shizuoka University

• Shioda M

  Depertment Of Physiological Chemistry And Nutrition Faculty Of Medicine University Of Tokyo

• Shioda M

  Kumamoto Univ. Kumamoto Jpn

• Shioda Masaki

  Department Of Biological Science Faculty Of Science Kumamoto University

• Ikegami S

  Nagahama Inst. Of Bio-science And Technol.

• Ikegami Susumu

  Department Of Applied Biochemistry Faculty Of Applied Biological Science

• Shimizu T

  Tanabe Seiyaku Co. Ltd. Osaka Jpn

• Kasahara Toshihiko

  Department Of Applied Biochemistry Hiroshima University

• Kajiyama N

  Kikkoman Corp. Chiba Jpn

• Ozaki Yoshihiro

  Department Of Applied Biochemistry Hiroshima University

• Shimizu Takahiko

  Department Of Aging Control Medicine Juntendo University Graduate School Of Medicine

• IKEGAMI Susumu

  Department of Agricultural Chemistry, University of Tokyo

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