Enzymatic Synthesis of β-Lactam Antibiotics and N-Fatty-Acylated Amino Compounds by the Acyl-Transfer Reaction Catalyzed by Penicillin V Acylase from Streptomyces mobaraensis
スポンサーリンク
概要
- 論文の詳細を見る
Penicillin V acylase from Streptomyces mobaraensis (Sm-PVA) showed high acyl-transfer activity in reactions using methyl esters of carboxylic acid (acyl donor) and amino compounds (nucleophile), to produce the corresponding amides. Moreover, Sm-PVA had broad substrate specificity, as indicated by the fact that it catalyzed the efficient synthesis of β-lactam antibiotics, capsaicin derivatives, and N-fatty-acyl-amino acid/N-fatty-acyl-peptide derivatives.
- 社団法人 日本農芸化学会の論文
- 2007-06-23
著者
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Imanaka Hiroyuki
Graduate School of Natural Science and Technology, Okayama University
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Imamura Koreyoshi
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
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Nakanishi Kazuhiro
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
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Imanaka Hiroyuki
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
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KOREISHI Mayuko
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
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Nakanishi K
Department Of Bioscience And Biotechnology Faculty Of Engineering Okayama University
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Nakanishi Kazuhiro
Division Of Chemistry And Biochemistry Graduate School Of Natural Science And Technology Okayama Uni
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Nakanishi Kazuhiro
Department Of Anesthesia Nippon Medical School
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TANI Kazuha
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
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ISE Yuuichi
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
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Imamura Koreyoshi
Graduate School Of Natural Science And Technology Okayama University
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Imamura Koreyoshi
Department Of Bioscience And Biotechnology Faculty Of Engineering Okayama University
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Imanaka Hiroyuki
Graduate School Of Natural Science And Technology Okayama University
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Nakanishi Kazuhiro
Graduate School Of Natural Science And Technology Okayama University
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Ise Yuuichi
Department Of Bioscience And Biotechnology Faculty Of Engineering Okayama University
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Koreishi Mayuko
Division Of Chemistry And Biochemistry Graduate School Of Natural Science And Technology Okayama Uni
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Nakanishi Kazuhiro
Deparment Of Food Science And Technology Faculty Of Agriculture Kyoto University
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Tani Kazuha
Department Of Bioscience And Biotechnology Faculty Of Engineering Okayama University
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