Novel Cyclic Peptide, Epichlicin, from the Endophytic Fungus, Epichloe typhina
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概要
- 論文の詳細を見る
The novel cyclic peptide, epichlicin, was isolated from Epichloe typhina, an endophytic fungus of the timothy plant (Phleum pretense L.). Its structure was determined by NMR studies and by mass spectrometry. Enantiomers of 3-amino tetradecanoic acid, a constituent amino acid of epichlicin, were synthesized as authentic standards. The stereochemistry of each amino acid was elucidated through a combination of the advanced Marfey method and chemical manipulation. Epichlicin showed inhibitory activity toward the spore germination of Cladosporium phlei, a pathogenic fungus of the timothy plant at an IC50 value of 22 nM.
- 社団法人 日本農芸化学会の論文
- 2007-06-23
著者
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MATSUURA Hideyuki
Laboratory of Bioorganic Chemistry, Division of Applied Bioscience, Graduate School of Agriculture,
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Matsui Hirokazu
Department of Bioscience and Chemistry, Faculty of Agriculture, Hokkaido University
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Nabeta Kensuke
Hokkaido Univ. Sapporo Jpn
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Nabeta Kensuke
Laboratory Of Bioorganic Chemistry Division Of Applied Life Science Graduate School Of Agriculture H
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Matsui H
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Yada Hiroshi
National Food Research Institute, National Agriculture and Food Research Organization
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Yada Hiroshi
National Food Research Institute
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Matsuura Hideyuki
Laboratory Of Bioorganic Chemistry Division Of Applied Life Science Graduate School Of Agriculture H
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Matsuura Hideyuki
Laboratory Of Bio-organic Chemistry Division Of Applied Bioscience Graduate School Of Agriculture Ho
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Yoshihara Teruhiko
Lab. Of Bioorganic Chemistry Div. Of Applied Bioscience Graduate School Of Agriculture Hokkaido Univ
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YOSHIHARA Teruhiko
Laboratory of Bio-organic Chemistry, Division of Applied Bioscience, Graduate School of Agriculture,
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TAKAHASHI Kosaku
Laboratory of Bio-organic Chemistry, Division of Applied Bioscience, Graduate School of Agriculture,
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MATSUURA Hideyuki
Research Faculty of Agriculture, Hokkaido University
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YOSHIHARA Teruhiko
Research Faculty of Agriculture, Hokkaido University
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Nabeta Kensuke
Laboratory Of Bioorganic Chemistry Division Of Applied Bioscience Research Faculty Of Agriculture Ho
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Matsuura Hideyuki
Graduate School Of Agriculture Hokkaido University
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Matsuura Hideyuki
Hokkaido Univ. Sapporo
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SETO Yoshiya
Laboratory of Bioorganic Chemistry, Division of Applied Bioscience, Research Faculty of Agriculture,
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Yada Hiroshi
National Food Research Institute National Agriculture And Food Research Organization
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KOGAMI Yasunori
Laboratory of Bioorganic Chemistry, Division of Applied Bioscience, Graduate School of Agriculture,
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Seto Yoshiya
Laboratory Of Bioorganic Chemistry Division Of Applied Bioscience Research Faculty Of Agriculture Ho
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Takahashi Kosaku
Div. Of Applied Bioscience Res. Fac. Of Agriculture Hokkaido Univ. Kita-9 Nishi-9 Kita-ku Sapporo 06
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Takahashi Kosaku
Laboratory Of Bio-organic Chemistry Division Of Applied Bioscience Graduate School Of Agriculture Ho
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Kogami Yasunori
Laboratory Of Bioorganic Chemistry Division Of Applied Bioscience Graduate School Of Agriculture Hok
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Yoshihara Teruhiko
Research Faculty Of Agriculture Hokkaido University
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Yoshihara Teruhiko
Laboratory Of Bio-organic Chemistry Division Of Applied Bioscience Graduate School Of Agriculture Ho
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Matsui Hirokazu
Lab. Of Biochemistry Div. Of Applied Bioscience Res. Fac. For Agriculture Hokkaido Univ.
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Seto Yoshiya
Laboratory Of Bioorganic Chemistry Division Of Applied Bioscience Research Faculty For Agriculture Hokkaido University
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