Isolation of Antibabesial Compounds from Brucea javanica, Curcuma xanthorrhiza, and Excoecaria cochinchinensis
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概要
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One new curcuminoid, 3′-demethoxycyclocurcumin (1), was isolated from Curcuma xanthorrhiza as an antibabesial compound, together with p-hydroxybenzaldehyde (2) and cleomiscosin A (3) from Brucea javanica and (+)-epiloliolide (4) from Excoecaria cochinchinensis. The antibabesial activities were examined in vitro, and compounds 1–4, and diminazene aceturate were studied with IC50 values of 16.6, 7.6, 15.6, 10.0, and 0.6 μg/ml, respectively.
- 社団法人 日本農芸化学会の論文
著者
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MATSUURA Hideyuki
Laboratory of Bioorganic Chemistry, Division of Applied Bioscience, Graduate School of Agriculture,
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KATAKURA Ken
Laboratory of Parasitology, Department of Disease Control, Graduate School of Veterinary Medicine, H
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Nabeta Kensuke
Hokkaido Univ. Sapporo Jpn
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Nabeta Kensuke
Laboratory Of Bioorganic Chemistry Division Of Applied Life Science Graduate School Of Agriculture H
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Yamasaki Masahiro
Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Sciences, Graduate Sch
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YAMADA Kazuaki
Laboratory of Bioorganic Chemistry, Division of Applied Bioscience, Research Faculty of Agriculture,
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