Effect of Dietary Supplementation of n-3 Polyunsaturated Fatty Acids (PUFA) on Red Blood Cell Deformability and Blood Viscosity in Rats
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概要
- 論文の詳細を見る
The effect of dietary fish oil containing eicosapentaenoic acid and docosahexaenoic acid on blood viscosity was compared with that of corn oil. Male Sprague-Dawley rats at 4 weeks old were fed the experimental diets for 3 weeks, and the blood viscosity of the two groups was compared with a Micro Channel Array Flow Analyzer (MC-FAN). The viscosity of heparinized whole blood of the fish oil group was significantly lower than that of the corn oil group, although no significant difference was observed in the deformability of the red blood cells. Frequent platelet aggregations were observed only in the corn oil group in the images of a videocamera equipped with a MC-FAN. The arachidonic acid level in phospholipids of the plasma containing platelet was higher in the corn oil group than in the fish oil group. These findings suggest that the dietary fish oil improved the whole blood viscosity mainly by retarding the platelet aggregation ability, not by increasing the deformability of red blood cell membrane.
- 日本油化学会の論文
- 2003-08-01
著者
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Fujimoto Kenshiro
Graduate School Of Agricultural Science Tohoku University
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Kimura Fumiko
東北大学 農学研究科
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Kimura Fumiko
Grad. Sch. Agr. Sci. Tohoku Univ.
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Endo Y
School Of Bionics Tokyo University Of Technology
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Endo Yasushi
東北大学 大学院農学研究科
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Endo Yasushi
Laboratory of Food and Bio-molecular Science, Graduate School of Agricultural Science, Tohoku Univer
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KIMURA FUMIKO
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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FUJIMOTO KENSHIRO
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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KIKUCHI Yuji
Microchannel Array Technology Team, National Food Research Institute
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WATANABE Nakamichi
Laboratory of Food and Bio-molecular Science, Graduate School of Agricultural Science, Tohoku Univer
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FUNAYAMA Katsura
Laboratory of Food and Bio-molecular Science, Graduate School of Agricultural Science, Tohoku Univer
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Yasushi Endo
Grakuate School Of Agricultural Science Tohoku University
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Yasushi Endo
Laboratory Of Food And Bio-molecular Science Graduate School Of Agricultural Science Tohoku Universi
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Endo Y
Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku University
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Endo Yasushi
Faculty Of Agriculture Tohoku University
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Kimura F
Graduate School Of Agricultural Science Tohoku University
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Fujimoto K
Graduate School Of Agricultural Science Tohoku University
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Fujimoto Kenshiro
Faculty Of Agriculture Tohoku University
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Kimura F
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Kimura Fumiko
Laboratory Of Food And Bio-molecular Science Graduate School Of Agricultural Science Tohoku Universi
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Kikuchi Y
Microchannel Array Technology Team National Food Research Institute
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Kikuchi Yuji
Microchannel Array Technology Team National Food Research Institute
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Funayama Katsura
Riken Vitamin Co.
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FUJIMOTO Kenshiro
Laboratory of Food and Bio-molecular Science, Graduate School of Agricultural Science, Tohoku University
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Watanabe Nakamichi
Laboratory of Food and Bio-molecular Science, Graduate School of Agricultural Science, Tohoku University
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