Noise Analysis of Si-Based Planar-Type Ion-Channel Biosensors
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概要
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A micropore with a diameter of 50–100 μm was formed, which penetrated a silicon on insulator (SOI) substrate and a Teflon substrate. The single-ion-channel current of gramicidin A (g-A) was measured for the planar lipid bilayer with reconstructed g-A formed in this micropore. The background noise in the SOI substrate was almost at an equivalent level to that in the Teflon substrate. It can be concluded from the noise analysis that a noise characteristic of the same level as that of the Teflon substrate or the glass substrate can be achieved for the Si substrate by controlling the substrate structure in the vicinity of the micropore with a wide range of pore diameters.
- 2006-12-25
著者
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Seki Shu
The Institute Of Scientific And Industrial Research
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Tagawa Seiichi
The Institute Of Scientific And Industrial Research
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TERO Ryugo
Institute for Molecular Science
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Zhang Zheng
The Graduate University For Advanced Studies
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Urisu Tsuneo
Insti. Mol. Sci. Dept. Vacuum Uv Photosci
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Nakao Satoshi
Institute For Molecular Science
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UNO Hidetaka
Institute for Molecular Science
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SUZUI Mitsukazu
Institute for Molecular Science
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NONOGAKI Youichi
Institute for Molecular Science
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Nonogaki Youichi
Institute for Molecular Science, Myodaiji, Okazaki, Aichi 444-8585, Japan
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Oiki Shigetoshi
Facul. Med. Sci., Univ. Fukui
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Oiki Shigetoshi
Faculty of Medical Sciences, University of Fukui, 23-3 Matsuokashimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan
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Suzui Mitsukazu
Institute for Molecular Science, Myodaiji, Okazaki, Aichi 444-8585, Japan
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Urisu Tsuneo
Institute for Molecular Science, Myodaiji, Okazaki, Aichi 444-8585, Japan
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Zhang Zheng
The Graduate University for Advanced Studies, Myodaiji, Okazaki, Aichi 444-8585, Japan
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Nakao Satoshi
Institute for Molecular Science, Myodaiji, Okazaki, Aichi 444-8585, Japan
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