Adenosine triphosphate facilitates the Na+-K+ pump of frog skeletal muscle fibres.
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概要
- 論文の詳細を見る
Effects of adenosine triphosphate (ATP) and dibutyryl cyclic adenosine monophosphate (dbc AMP) on the Na<SUP>+</SUP> -K<SUP>+</SUP> pump of cell membrane were studied by testing the effects of these nucleotides on the <SUP>22</SUP>Na<SUP>+</SUP>-efflux from frog skeletal muscle fibres. The rate coefficient of <SUP>22</SUP>Na<SUP>+</SUP>-efflux was found to be significantly increased by ATP 3 mM. Dbc AMP 3 mM showed no demonstrable effect. These results support the concept that ATP facilitates the electrogenic Na<SUP>+</SUP> pump, but do not support the concept that the electrogenic Na<SUP>+</SUP> pump is stimulated by cyclic AMP.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Hasuo Hiroshi
Department Of Anesthesiology Nagasaki University School Of Medicine
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Kaibara Kozue
Department Of Biological Substances And Life Science Faculty Of Engineering Kyushu Kyoritsu Universi
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Koketsu Kyozo
Department Of Physiology Kurume University School Of Medicine
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Akasu Takashi
Department Of Physiology Kurume University School Of Mediceine
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Nishimura Toshihiko
Department Of Neurosurgery Fuchu Metropolitan Hospital
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Tokimasa Takayuki
Department Of Physiology
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Hirai Keiji
Department Of Architecture Nishinippon Institute Of Technology
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KOJIMA MIKIE
Department of Chemistry, Faculty of Science, Kyushu University
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MIYAOAWA MICHIKO
Department of Physiology, Kurume University School of Medicine
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YAMADA MICHIHISA
Department of Physiology, Kurume University School of Medicine
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TOKIMASA TAKAYUKI
Department of Internal Medicine and Department of Physiology, Kurume University School of Medicine
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