Effects of Barium on Delayed Rectifier Potassium Current in Bullfrog Sympathetic Neurons Pretreated with Wortmannin
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概要
- 論文の詳細を見る
The effect of barium (1 mM) on a delayed rectifier-type potassium current was examined in bullfrog sympathetic neurons. An M-type potassium current was eliminated by pretreatment of the cells with a microbial product, wortmannin (10μM). An A-type potassium current was continuously inactivated by setting a holding potential at -65 mV. In treated cells (n=10), the delayed rectifier at 0 mV averaged 2200±107 pA in the presence of barium (1 mM) as compared to 2308±110 pA in the controls, and 2085±103 pA after washing out the barium. It is concluded that the delayed rectifier is insensitive to barium blockage in amphibian autonomic neurons.
- 東海大学の論文
著者
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Tokimasa Takayuki
Department Of Physiology School Of Medicine Tokai University
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Inomoto Chie
Department Of Pathology Tokai University School Of Medicine
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Inomoto Chie
Department Of Physiology Tokai University School Of Medicine
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Tokimasa Takayuki
Department Of Physiology
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