A comparative study on features of magnetic resonance imaging and pathological findings in metastatic hepatic tumors.

概要

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A comparative study on features of magnetic resonance imaging (MRI) and histopathology of 117 metastatic hepatic tumors obtained from 28 autopsy cases was investigated. On the basis of the morphology of T2 weighted pulse sequences, they could be divided into nodular type (99%) and massive type (1%), and then the former group could be subdivided into homogenous (21%), uneven (61%) and bull's eye type (17%). Homogenous type apparently tended to be smaller than 1.0cm in diameter, by the contrast uneven and bull's eye types tended to be larger than 3.0cm in diameter. Histopathologically, solid carcinomas with if any a small amount of necrosis or fibrosis in homogenous type, carcinomas admixed with rather large amounts of necrosis, fibrosis or hemorrhage in uneven type and carcinoma nodules accompanied by massive necrosis in their center in bull's eye type were found. There was no significant correlation among the classification, the primary site and the histologic type of the tumor. High intensity areas around the tumors in 6 lesions (5%) and "ring shaped" low intensity areas in 5 lesions (4%) were noticed. We have discussed them, too. In addition, quantitative analysis of iron, copper and zinc in the hepatic tissue were performed to investigate the relation between those concentrations and MRI features.