Effects of Coronary Vasodilators on Large and Small Coronary Arteries of Dogs
スポンサーリンク
概要
- 論文の詳細を見る
Using the isolated perfused heart preparation supported by a donor the effects of vasodilators on the large conductance artery were studied and were compared with those on the small resistive artery and arterioles. Nitroglycerin produced a preferential dilatation of the large conductance artery, while dipyridamole produced a dilatation only of the small resistive artery and arterioles.Among the "calcium antagonistic" vasodilators tested, only diltiazem produced a dilatation of the large conductance artery, verapamil and nifedipine producing a dilatation only of the samll resistive artery and arterioles. These findings indicate that the mechanism of contraction of the large conductance artery is different from that of the small resistive artery and arterioles.
- International Heart Journal刊行会の論文
著者
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IMAI Shoichi
Department of Pharmacology, Niigata University School of Medicine
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Imai Shoichi
Department Of Phamacology Niigata University School Of Medicine
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NAKAGAWA YOSHITO
Department of Pharmacy, Yamagata University Hospital
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Katano Yumi
Department Of Cardiology Pulmonology And Nephrology Yamagata University School Of Medicine
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TAKEDA Keisuke
Department of Applied Chemistry, Faculty of Engineering, Gunma University
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Nakagawa Yoshito
Department Of Pharmacology Niigata University School Of Medicine
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Takeda Keisuke
Department Of Applied Chemistry Faculty Of Engineering Gunma University
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TAKEDA Keisuke
Department of Pharmacology, Niigata University School of Medicine
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