Studies of Coumarins from the Chinese Drug Qianhu, XXVII : Structure of a New Simple Coumarin Glycoside from Bai-Hua Qianhu, Peucedanum praeruptorum
スポンサーリンク
概要
- 論文の詳細を見る
A new simple coumarin glycoside, named praeroside VI (1), along with six known coumarins, were isolated from an aqueous extract of Bai-Hua Qianhu, the root of Peucedanum praeruptorum DUNN. (Umbelliferae). Spectroscopic analysis and chemical studies were carried out to investigate the structure of the new coumarin, which was concluded to be 1. Additionally, two simple glycosidic coumarins and four simple nonglycosidic coumarins were identified as apiosylskimmin (2), hymexelsin (3), umbelliferone (4), scopoletin (5), isofraxidin (6) and 8-carboxy-7-hydroxy coumarin (7), respectively. This is the first reported identification of compound 7 as a constituent of plant materials.
- 公益社団法人日本薬学会の論文
- 2008-09-01
著者
-
Ishii Hirotaka
Department Of Physiology Nippon Medical School
-
Ishii Hirotaka
Department Of Natural Medicine And Phytochemistry Meiji Pharmaceutical University:(present Office)fo
-
BABA Masaki
Department of Natural Medicine and Phytochemistry, Meiji Pharmaceutical University
-
OKUYAMA Toru
Department of Natural Medicine and Phytochemistry, Meiji Pharmaceutical University
-
OKADA Yoshihito
Department of Natural Medicine and Phytochemistry, Meiji Pharmaceutical University
-
BABA Masaki
明治薬科大学天然薬物学教室
-
Baba Masaki
Department Of Natural Medicine And Phytochemistry Meiji Pharmaceutical University
-
Okada Y
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
-
Okuyama Toru
Department Of Natural Medicine And Phytochemistry Meiji Pharmaceutical University
-
Okuyama T
Department Of Natural Medicine & Phytochemistry Meiji Pharmaceutical University
-
Okada Yoshihito
Department Of Pharmacognosy And Phytochemistry Meiji College Of Pharmacy
-
Ogino Yoshio
The Third Department Of Internal Medicine Yeikyo University School Of Medicine
-
Okuyama Toru
Meiji Pharmaceutical Univ. Tokyo Jpn
-
Okada Yoshihito
Department Of Natural Medicine And Phytochemistry Meiji Pharmaceutical University
-
Ogino Y
Teikyo Univ. School Of Medicine Chiba
関連論文
- Synthesis of Endomorphin-2Analogues Containing Piperidinecarboxylic Acid (Pip) and 2-Azetidinecarboxylic Acid (Aze)
- Synthesis and Biological Activity of Endomorphin-2 Analogues Containing Pro Mimics
- Synthesis and Binding Activities of Endomorphin Analogs Containing 1-Aminocyclopropane-1-carboxylic Acid
- Inhibitory Effect of Chalcone Derivatives on Recombinant Human Aldose Reductase
- Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E_2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development
- Studies on Cancer Chemoprevention by Traditional Folk Medicines XXIV.^ Inhibitory Effect of a Coumarin Derivative, 7-Isopentenyloxycoumarin, against Tumor-Promotion
- Gene structures, biochemical characterization and distribution of rat melatonin receptors
- Rat GnRH Neurons Exhibit Large Conductance Voltage- and Ca^-Activated K^+ (BK) Currents and Express BK Channel mRNAs
- Different Roles of Two Consecutive Leucine Residues in a Receptor-Tethered Ligand Peptide (SFLLRNP) in Thrombin Receptor Activation
- Studies of the Constituents of Astragalus membranaceus BUNGE. III. Structure of Triterpenoidal Glycosides, Huangqiyenins A and B, from the Leaves
- Differential Receptor Recognition by Dmt-Containing Enkephalin Dimers Cross-Linked by Phenylenediamines
- Deprotection of the Indole (N^)_Formyl (For) Group on Tryptophan Employing a New Reagent, N,N'-Dimethylethylendiamine (DMEDA) in an Aqueous Solution
- Studies of Coumarins from the Chinese Drug Qianhu, XXVII : Structure of a New Simple Coumarin Glycoside from Bai-Hua Qianhu, Peucedanum praeruptorum
- Application of liquid chromatography-tandem mass spectrometry for the determination of opioidmimetics in the brain dialysates from rats treated with opioidmimetics intraperitoneally
- Effects of Isoliquirithigenin on the Development of Preneoplastic Liver Lesions Caused by a Choline-Deficient, L-Amino Acid-Defined Diet and on the Urinary Bladder Carcinogenesis by N-Butyl-N-(4-hydroxybutyl)nitrosamine in Rats
- Enantioselective Synthesis of a Phenylalanine Library Containing Alkyl Groups on the Aromatic Moiety : Confirmation of Stereostructure by X-Ray Analysis
- The Antiproliferative Activities of Somatostatin Analogs on Various Tumor Cells
- Roles of Each Component of μ-Opioid Ligands Containing Dmt-Pyrazinones
- Studies on the Mechanism of 1,2-Dihydropyrazin-2-one Ring Formation from Dipeptidyl Chloromethyl Ketone and Its Chemical Properties : Immediate Deamination during Catalytic Hydrogenation
- Synthesis and Bioactivity of Novel Type Pyrazinone Ring-Containing μ-Opioid Ligands
- Generation of a Selective Agonist for Mu-Opioid Receptors by the Dimerization of 2', 6'-Dimethyl-L-Tyrosine through Pyrazinone
- Synthesis of Somatostatin Analogs and Their Antitumor Activities
- The Structure-Activity Relationship of Dmt-NH-X
- Synthesis of New Pyrazinone Ring-Containing Opioid Mimetics and Studies on Their Structure-Activity Relationship
- Stereoselective Synthesis of Unique L-Tyrosine Analogs : Development of Novel μ-Opioid Receptor Ligands
- Synthesis of Opioid Mimetics Containing a Pyrazinone Ring and Their Activities
- Structure-Inhibitory Activity Relationship of Plasmin and Plasma Kallikrein Inhibitors^
- Isolation of Plasma Kallikrein by High Efficiency Affinity Chromatography and Its Characterization
- Structure-Inhibitory Activity Relationships of Plasmin and Plasma Kallikrein Inhibitors
- Binding Diversity of a Noncovalent-Type Low-Molecular-Weight Serine Protease Inhibitor and Function of a Catalytic Water Molecule : X-Ray Crystal Structure of PKSI-527-Inhibited Trypsin
- Chemical Constituents of the Style of Zea mays L. with Glycation Inhibitory Activity
- The Favorable Effect of Style of Zea mays L. on Streptozotocin Induced Diabetic Nephropathy(Pharmacognosy)
- A New Flavone C-Glycoside from the Style of Zea mays L. with Glycation Inhibitory Activity
- Relazant Effects of Pyranocoumarin Compounds Isolated from a Chinese Medical Plant, Bai-Hua Qian-Hu, on Isolated Rabbit Tracheas and Pulmonary Arteries
- Evaluation of the Trifluoromethanosulfonic Acid/Trifluoroacetic Acid/Thioanisole Cleavage Procedure for Application in Solid-Phase Peptide Synthesis
- Saponins Isolated from Allium chinense G. DON and Antitumor-promoting Activities of Isoliquiritigenin and Laxogenin from the Sama Drug
- Synthesis of Endomorphin-2 Analogues, Studies on Their Activities for Opioid Receptors, and Three Dimensional Structure
- Antitumor-promoting activity of diallyl pentasulfide; a constituent of garlic
- New Acetylenic Glucosides from Bidens bipinnata LINNE
- Two New Saponins, Congmuyenosides A and B, from the Leaves of Aralia elata Collected in Heilongjiang, China
- PC52 ANTITUMOR-PROMOTING ACTIVITY OF GARLIC EXTRACT
- CALCIUM ANTAGONIST-LIKE ACTIONS OF COUMARINS ISOLATED FROM "QIAN-HU" ON ANAPHYLACTIC MEDIATOR RELEASE FROM MAST CELL INDUCED BY CONCANAVALIN A
- Studies on the Stable Structure and Inhibitory Activity of Plasmin and Plasma Kallikrein Inhibitors Using the MM+ Force Field
- Synthesis of Cyclic Peptides with Agonist Activity for Melanocortin Receptors
- Effects of a Structured Psychiatric Intervention on Immune Function of Cancer Patients
- Persistent effects of a structured psychiatric intervention on breast cancer patients' emotions
- Persistence of the Benefits of a Structured Psychiatric Intervention for Breast Cancer Patients with Lymph Node Metastases
- The Role of Arginine in Thrombin Receptor Tethered-Ligand Peptide in Intramolecular Receptor Binding and Self-Activation
- Studies on Cancer Chemoprevention by Traditional Folk Medicines XXV.^ Inhibitory Effect of Isoliquiritigenin on Azoxymethane-Induced Murine Colon Aberrant Crypt Focus Formation and Carcinogenesis
- Comorbidity of depression among physically ill patients and its effect on the length of hospital stay
- General hospital psychiatry from the perspective of medical economics
- The n-Butanol Soluble Part of Style of Zea mays L. (Gramineae) Ameliorates both Hyper- and Hypoalgesia in Streptozotocin-induced Diabetic Rats
- Inhibitory Effect of Traditional Turkish Folk Medicines on Aldose Reductase (AR) and Hematological Activity, and on AR Inhibitory Activity of Quercetin-3-O-methyl Ether Isolated from Cistus laurifolius L.(Pharmacognosy)
- PC51 INHIBITION OF TUMOR PROMOTER-INDUCED PHENOMENA BY THEPRINCIPLES OBTAINED FROM ALLIUM SPP.
- HPLC analysis of coumarins in Turkish Seseli species (Umbelliferae)
- The Composition of Essential Oils from Seseli Species Growing in Turkey
- Coumarins from Seseli gummiferum Pall. ex Sm. subsp. corymbosum P. H. Davis
- Two New Megastigmanes from the Leaves of Cucumis sativus
- Search for Naturally Occurring Substances to Prevent the Complications of Diabetes. III : Studies on Active Substances from Gnaphalium affine D. DON
- Development of Potent and Selective Plasmin and Plasma Kallikrein Inhibitors and Studies on the Structure-Activity Relationship
- Structural Studies of [2',6'-Dimethyl-L-tyrosine^1]Endomorphin-2 Analogues Containing Proline Mimics
- A New Triterpenoid Isolated from Lagerstronemia speciosa (L.) PERS.
- Screening for Nicotine Dependence among Smoking-related Cancer Patients
- Studies on Index Compounds for HPLC Analysis of Glycyrrhiza flavescens Growing in Turkey
- Hematological Studied on Black Cumin Oil from the Seeds of Nigella sativa L.
- Voltage-gated Ca^ channel mRNAs and T-type Ca^ currents in rat gonadotropin-releasing hormone neurons
- Anticipatory nausea among ambulatory cancer patients undergoing chemotherapy : Prevalence, associated factors, and impact on quality of life
- Relationship between structure and P-glycoprotein inhibitory activity of dimeric opioid peptides containing the Dmt-Tic pharmacophore
- Protective Effect of Daidzein against Impairment of Learning and Memory Induced by Cerebral Ischemia-reperfusion in Mice
- A New Flavonoid Glycoside from Pituranthos tortuosus Desf, Benth & Hook
- Three New Saponins as Index Compounds of Glycyrrhiza flavescens BOISS. Growing in Turkey
- Studies on the Constituents of Astragalus membranaceus II. : Structure of Triterpenoidal Glycoside, Huangqiyenin D, from its Leaves
- Studies on Index Compounds for HPLC Analysis of Glycyrrhiza flavescens Growing in Turkey
- Coumarins from Seseli gummiferum Pall, ex Sin. subsp. corymbosum P. H. Davis
- The Composition of Essential Oils from Seseli Species Growing in Turkey
- Using Chitin Column Chromatography, Isolation of 24-Hydroperoxy-24-vinyl-cholesterol from Sargassaceae Seaweeds
- Inhibitory Effect of Some Wild Plants in Akita on Melanin Biosynthesis
- Naturally Occurring Substances for Prevention of Complications of Diabetes. IV : Screening of Seavegetables for Inhibitory Effect on Aldose Reductase.
- Studies on Constituents of Acanthopanax senticosus in China(Natural Medicine Note)
- Search for Naturally Occurring Substances for Prevention against the Complications of Diabetes : Inhibitory Effect on Aldose Reductase and Platelet Aggregation
- Flavonoid Glycosides of Lespedeza Species
- Studies on the Constituents of Scutellaria Species-2-High Performance Liquid Chromatography of Glucuronyflavonoids and Seasonal Variation of Their Contents in Scutellaria ikonnikovii Juz.(速報)
- Effects of Pd-Ia, a Component of Chinese Traditional Herb Bai-Hua Qian-Hu, on Ca^-Current and Action Potential Duration in Single Ventricular Cells of Guinea Pig Hearts
- Flavonoid Glycosides from the Leaves of Jasminum humile var. revolutum(Natural Medicine Notes)
- Search for Naturally Occurring Substances to Prevent the Complications of Diabetes. III. : Studies on Active Substances from Gnaphalium affine D. DON
- Studies on the Antitumor-Promoting Activity of Naturally Occurring Substances. III. : Structure of a New Coumarin and Anti-Tumor-Promoter Activity of Coumarins from Angelicae Radix
- Flavonoids from Syneilesis aconitifolia(Natural Medicine Note)