Total Synthesis of (6S,1'S,2'R)-6-(1',2'-Dihydroxypentyl)-4-methoxy-5,6-dihydropyrane-2-one (LL-P880β) and Its C_6-Epimer, a Fungal Metabolite from Penicillium sp.(Organic Chemistry)
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概要
- 論文の詳細を見る
A fungal metabolite, (6S,1'5',2'R)-6-(1',2'-dihydroxypentyl)-4-methoxy-5,6-dihydropyrane-2-one (LL-P880β, I), and its C_6-epimer (II) were synthesized by the chiron approach. The key intermediate, (25,3R)-2,3-dihydroxyhexanal derivative (3), was prepared from D-glucose as a chiral building block and reacted with the dianion of ethyl acetoacetate to complete the formal syntheses of I and II.
- 社団法人日本農芸化学会の論文
- 1990-09-23
著者
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Miyatake K
Osaka Prefecture Univ. Osaka Jpn
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Kirihata Mitsunori
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Ichimoto I
Department Of Applied Biochemistry College Of Agriculture University Of Osaka Prefecture
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Ichimoto Itsuo
Department Of Agricultural Chemistry College Of Agriculture
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Ueda Hiroo
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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OHTA Kazunari
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture
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Ohta Kazunari
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture:(present
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KIRIHATA Mitsunori
Department of Agricultual Chemistry, College of Agriculture, University of Osaka Prefecture
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