On the Diterpenoids of Andrographis paniculata : X-Ray Crystallographic Analysis of Andrographolide and Structure Determination of New Minor Diterpenoids
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概要
- 論文の詳細を見る
The crystal structure of andrographolide (8) was determined and the absoluted configuration at C-14,which was previously undecided, was established as R. Reexamination of the constituents of Andrographis paniculata NEES resulted in the isolation of three new diterpenoids of ent-labdane type, and rographanin, andropanoside, and 14-deoxy-12-methoxy-andrographolide, together with three known compounds, 14-deoxyandrographolide (4), neoandrographolide (5) and andrographolide (8). The structures of the new diterpenoids were determined to be 1,2,and 3 on the basis of spectral and chemical evidence.
- 社団法人日本薬学会の論文
- 1984-06-25
著者
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高石 喜久
徳島大院薬
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木戸 勝
大塚製薬
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木戸 勝
Laboratories Of Natural Product Chemistry Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd
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武田 美雄
Faculty of Integrated Arts and Sciences, University of Tokushima
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武田 美雄
徳島大総科
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藤多 哲朗
Faculty of Pharmaceutical Sciences, The University of Tokushima
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富士谷 隆二郎
Faculty of Pharmaceutical Sciences, The University of Tokushima
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高石 喜久
Faculty of Pharmaceutical Sciences, The University of Tokushima
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山田 敏英
Laboratories of Natural Products Chemistry, Otsuka Pharmaceutical Co., Ltd.
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三浦 厳
Laboratories of Natural Products Chemistry, Otsuka Pharmaceutical Co., Ltd.
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高石 喜久
Faculty Of Pharmaceutical Science Tokushima University
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武田 美雄
Faculty Of Integrated Arts And Sciences The University Of Tokushima
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富士谷 隆二郎
Faculty Of Pharmaceutical Sciences The University Of Tokushima
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三浦 厳
大塚製薬
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山田 敏英
大塚製薬
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藤多 哲朗
摂南大学薬学部
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藤多 哲朗
Faculty Of Pharmaceutical Sciences Kyoto University
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藤多 哲朗
Kyoto Pharmaceutical Univ. Kyoto Jpn
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Takeda Y
Fac. Of Integrated Arts And Sciences Univ. Of Tokushima
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Takeda Y
Faculty Of Integrated Arts And Sciences The University Of Tokushima
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高石 喜久
Faculty of Integrated Arts and Sciences, University of Tokushima
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