Syntheses of Two Microbial Metabolites, 5-Chloro-3,4-dihydro-8-hydroxy-6-methoxy-3-methylisocoumarin and 8-Hydroxy-6-methoxy-3-methylisocoumarin
スポンサーリンク
概要
- 論文の詳細を見る
The racemate of 5-chloro-3,4-dihydro-8-hydroxy-6-methoxy-3-methylisocoumarin (I), a fungal metabolite of Periconia macrospinosa, was synthesized from 6-chloro-3,5-dimethoxyhomophthalic acid (III) via compounds IV, VI, VII and VIII. Catalytic hydrogenation of V resulted in dechlorination, yielding 6-methoxy-8-hydroxy3-methylisocoumarin (II), another natural product from Streptomyces mobaraensis.
- 公益社団法人日本薬学会の論文
- 1980-05-25
著者
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河合 賢一
星薬大
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野沢 幸平
星薬科大学
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山田 美紀子
Faculty Of Pharmaceutical Sciences Chiba University
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野沢 幸平
Hoshi College of Pharmacy
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山田 美紀子
Hoshi College of Pharmacy
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河合 賢一
Hoshi College of Pharmacy
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中嶋 洋一
Hoshi College of Pharmacy
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