Studies on Fungal Products. IX. : Dethiosecoemestrin, a New Metabolite Related to Emestrin, from Emericella striata
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概要
- 論文の詳細を見る
In the course of searching for metabolites related to emestrin (3) from Emericella striata (80-NE-22), dethiosecoemestrin (1) was isolated from the methylene chloride extract of the culture filtrate. The tremorgenic mycotoxin, paxilline (6), was also isolated from the mycelial extract. The structure of dethiosecoemestrin was established on the basis of the chemical and spectroscopic evidence as 1. It is postulated that dethiosecoemestrin was biogenetically derived from emestrin.Dethiosecoemestrin was easily degradated to violaceic acid (5). The antimicrobial activity of dethiosecoemestrin was examined.
- 公益社団法人日本薬学会の論文
- 1986-06-25
著者
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河合 賢一
Faculty of Pharmaceutical Sciences, University of Tokyo
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野沢 幸平
Faculty of Pharmaceutical Sciences, Hoshi University
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仲嶋 正一
Faculty of Pharmaceutical Sciences, Hoshi University
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宇田川 俊一
National Institute of Hygienic Sciences
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河合 賢一
Faculty Of Pharmaceutical Sciences Hoshi University
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野沢 幸平
星薬科大学
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宇田川 俊一
Research Center For Pathogenic Fungi And Microbial Toxicoses Chiba University
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Kawai Koji
Basic Research Laboratories Toray Industries Inc.
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瀬谷 秀之
Faculty of Pharmaceutical Sciences, Hoshi University
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仲嶋 正一
Faculty Of Pharmaceutical Sciences Hoshi University
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Nakajima S
Shionogi Research Laboratories Shinogi & Co. Ltd.
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瀬谷 秀之
Faculty Of Pharmaceutical Sciences Hoshi University
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