Synthesis of 6-Chloro-3,5-dimethoxyhomophthalic Acid, a Key Intermediate for the Synthesis of Radicicol and Natural Isocoumarin
スポンサーリンク
概要
- 論文の詳細を見る
6-Chloro-3,5-dimethoxyhomophthalic acid (I) was synthesized as a key intermediate for the synthesis of radicicol and isocoumarins of natural origin, via a sequence of reactions including cyclization of 3-(2-chloro-3,5-dimethoxyphenyl) propionic acid (XIV) to 4-chloro-5,7-dimethoxyindan-1-one (XVI) and oxidative decomposition of methyl (4-chloro-2,3-dihydro-5,7-dimethoxy-1-oxo-1H-inden-2-ylidene) hydroxyacetate (XVII) to I as key steps.
- 公益社団法人日本薬学会の論文
- 1980-04-25
著者
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野沢 幸平
星薬科大学
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Kawai Koji
Basic Research Laboratories Toray Industries Inc.
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Nakajima S
Shionogi Research Laboratories Shinogi & Co. Ltd.
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