Studies on Radioimmunoassay of Metanephrine
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概要
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Antigens of 3-O-methylcatecholamines (metanephrine, normetanephrine, 3-methoxy-tyramine) were prepared, keeping the methoxyl and hydroxyl groups of the benzene ring and the side chain intact. Rabbits were immunized with the metanephrine antigen and sufficient antiserum to develop a specific radioimmunoassay of metanephrine was obtained. The detection limit of metanephrine in the radioimmunoassay was 0.03 pmol. The radioimmunoassay was useful for the measurement of urinary metanephrine and of rat liver catechol-O-methyltransferase activity.
- 公益社団法人日本薬学会の論文
- 1980-10-25
著者
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田村 善蔵
Faculty of Pharmaceutical Sciences, University of Tokyo
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田村 善蔵
東大薬
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白幡 晶
Faculty Of Pharmaceutical Sciences University Of Tokyo:(present Address)tokyo Biochemical Research I
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吉岡 正則
Faculty Of Pharmaceutical Sciences University Of Tokyo
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田村 善蔵
Faculty Of Pharmaceutical Sciences University Of Tokyo
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松下 操
Faculty of Pharmaceutical Sciences, University of Tokyo
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松下 操
Faculty Of Pharmaceutical Sciences University Of Tokyo
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