Gas Chromatography of Catecholamines using Dimethyl Sulfoxide as an Effective Solvent for Trimethylsilylation.
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概要
- 論文の詳細を見る
Separation of catecholamines by gas chromatographic technique requires the preparation of suitable derivatives. A procedure has been developed which involved the treatment of amine mixtures with hexamethyldisilazane in dimethyl sulfoxide followed by the addition of an aliphatic ketone. Hydroxyl groups are converted into trimethylsilyl ether and primary amines are converted into Schiff bases. Secondary amino group remains unchanged. The separations were carried out with a 7% DC 1107 column. Catecholamines extracted from bovine adrenal medulla were separated and estimated under these conditions and good reproducible data were obtained.
- 公益社団法人日本薬学会の論文
- 1967-10-25
著者
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田村 善蔵
Faculty of Pharmaceutical Sciences, University of Tokyo
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河合 聰
Faculty of Pharmaceutical Sciences, University of Tokyo
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田村 善蔵
Faculty Of Pharmaceutical Sciences University Of Tokyo
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田村 善蔵
Pharmaceutical Institute School Of Medicine Keio University
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河合 聰
Faculty Of Pharmaceutical Sciences University Of Tokyo
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河合 聡
Pharmaceutical Laboratory School Of Medicine Keio University
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