New Steroidal Saponins from the Bulbs of Allium giganteum Exhibiting Potent Inhibition of cAMP Phosphodiesterase Activity
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概要
- 論文の詳細を見る
A new spirostanol saponin and two new furostanol saponins were isolated from the fresh bulbs of Allium giganteum together with several known saponins. The structures of the new compounds were determined on the basis of spectroscopic data, the products formed on hydrolysis and by comparing their properties with those of known compounds. The isolated saponins and their derivatives were evaluated for inhibitory activity by examining their action on cAMP phosphodiesterase as a primary screening test to identify new medicinal agents.
- 社団法人日本薬学会の論文
- 1994-03-15
著者
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指田 豊
東京薬大・薬・漢方資源応用
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三巻 祥浩
東京薬大・薬・漢方資源応用
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大本 太一
School of Pharmaceutical Sciences, Toho University
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二階堂 保
School of Pharmaceutical Sciences, Toho University
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二階堂 保
東邦大学薬学部
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三巻 祥浩
Tokyo College of Pharmacy
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指田 豊
Tokyo College of Pharmacy
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大本 太一
東邦大薬
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松本 勝己
Tokyo College of Pharmacy
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松本 勝己
School Of Pharmacy Tokyo University Of Pharmacy And Life Science
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Mimaki Yoshihiro
Lab. Of Medicinal Plant Sci. School Of Pharmacy Tokyo Univ. Of Pharmacy And Life Sci. Jpn
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Satomi Y
National Cancer Center Res. Inst. Tokyo Jpn
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Sashida Y
School Of Pharmacy Tokyo University Of Pharmacy And Life Science
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