A NEW APPROACH TO THE SYNTHESIS OF OPTICALLY ACTIVE PSEUDO-SUGAR AND PSEUDO-NUCLEOSIDE -SYNTHESES OF PSEUDO-α-D-ARABINOFURANOSE, (+)-CYCLARADINE, AND (+)-1,PSEUDO-β-D-ARABINOFURANOSYLURACIL FROM D-ARABINOSE -
スポンサーリンク
概要
- 論文の詳細を見る
An optically active pseudo-sugar, pseudo-α-D-arabinofuranose, was synthesized from D-arabinose in favorable overall yield by using a stereoselective formation of branched nitropyranose as the key step.Furthermore, two biologically active pseudo-β-D-arabinofuranosylnuleosides, (+)-cyclaradine and (+)-1-pseudo-β-D-arabinofuranosyluracil, were synthesized via Michael-type reactions of nucleic acid bases and a nitrocyclopentene derivative which was prepared from a synthetic intermediate of pseudo-D-arabinofuranose.
- 公益社団法人日本薬学会の論文
- 1993-03-15
著者
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吉川 雅之
Kyoto Pharmaceutical Univ.
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村上 啓寿
Kyoto Pharmaceutical University
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北川 勲
Faculty Of Pharmaceutical Sciences Osaka University
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畠山 祥子
Kyoto Pharmaceutical University
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井上 泰尚
Kyoto Pharmaceutical University
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