Chemistry of O-Silylated Ketene Acetals : A Stereoselective Synthesis of Optically Active Carbapenem Antibiotics, (+)-Thienamycin and (+)-PS-5
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概要
- 論文の詳細を見る
A stereoselective synthesis of the chiral thienamycin intermediate (16) involving a diastereoselective Michael addition and a silicon-induced Pummerer-type reaction is described. In a similar way, the key intermediate for(+)-PS-5 was also prepared from 4-(phenylsulfinylmethyl)butanamide (21).
- 社団法人日本薬学会の論文
- 1992-01-25
著者
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北 泰行
Faculty of Pharmaceutical Sciences, Osaka University
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北 泰行
大阪大学大学院薬学研究科
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北 泰行
大阪大学薬学部
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Kita Yasuyuki
Graduate School Of Pharmaceutical Sciences Osaka University Yamadaoka
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田村 修
Faculty of Pharmaceutical Sciences, Osaka University
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三木 隆
Faculty Of Pharmaceutical Sciences Osaka University
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柴田 哲男
Faculty of Pharmaceutical Sciences, Osaka University
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竹村 由美子
Faculty of Pharmaceutical Sciences, Osaka University
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田村 修
Faculty Of Pharmaceutical Sciences Osaka University
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田村 修
Faculty Of Pharmaceutical Sciences Kanazawa University
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竹村 由美子
Faculty Of Pharmaceutical Sciences Osaka University
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北 泰行
Faculty Of Pharmaceutical Sciences Osaka University
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