ORGANIC SYNTHESIS UTILIZING BECKMANN FRAGMENTATION : ASYMMETRIC CARBON-CARBON BOND FORMATION VIA CHIRAL ACETAL INTERMEDIATES
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概要
- 論文の詳細を見る
Treatment of racemic α-methoxycycloalkanone oxime acetates 1 with (2R, 4R)-2,4-bistrimethyl-silyloxypentane in the presence of a catalytic amount of trimethylsilyl triflate (TMSOTf) afforded the chiral acetal intermediates 3,which were reacted with silicon-containing nucleophiles to give the chiral ω-cyano compounds 4,in a one-pot operation.
- 社団法人日本薬学会の論文
- 1992-11-25
著者
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北 泰行
Faculty of Pharmaceutical Sciences, Osaka University
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北 泰行
大阪大学大学院薬学研究科
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北 泰行
大阪大学薬学部
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山中 武志
Faculty Of Pharmaceutical Sciences Osaka University
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藤岡 弘道
大阪大学大学院薬学研究科
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藤岡 弘道
Faculty Of Pharmaceutical Sciences Osaka University
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Kita Yasuyuki
Graduate School Of Pharmaceutical Sciences Osaka University Yamadaoka
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北川 英俊
Faculty of Pharmaceutical Sciences, Osaka University
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北川 英俊
Faculty Of Pharmaceutical Sciences Osaka University
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北 泰行
Faculty Of Pharmaceutical Sciences Osaka University
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