An Efficient p-Thiocyanation of Phenols and Naphtols Using a Reagent combination of Phenyliodine Dichloride and Lead(II) Thiocyanate

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概要

• 論文の詳細を見る

• A combination of PhICl_2 and Pb(SCN)_2 is effective for the p-selective thiocyanation of various types of p-unsubstituted phenols and naphthols 1 to give p-thiocyanatophenols and naphthols 3. The reaction proceeded at 0℃ to room temperature in good to quantitative yields. Twenty-five examples are given, in which various functional groups, such as chloro, allyl, carbonyl, ester, amide, and primary hydroxyl groups, are shown to be compatible with this reaction.

• 社団法人日本薬学会の論文
• 1997-12-15

著者

• 北 泰行

  大阪大学大学院薬学研究科

• 北 泰行

  大阪大学薬学部

• 赤井 周司

  大阪大学大学院薬学研究科

• Kita Yasuyuki

  Graduate School Of Pharmaceutical Sciences Osaka University Yamadaoka

• Egi Masahiro

  School Of Pharmaceutical Sciences University Of Shizuoka

• KITA Yasuyuki

  Faculty of Pharmaceutical Sciences, Osaka University

• TAKEDA Yoshifumi

  Faculty of Pharmaceutical Sciences, Osaka University

• OKUNO Takayuki

  Faculty of Pharmaceutical Sciences, Osaka University

• EGI Masahiro

  Faculty of Pharmaceutical Sciences, Osaka University

• IIO Kiyosei

  Faculty of Pharmaceutical Sciences, Osaka University

• KAWAGUCHI Ken-ichi

  Faculty of Pharmaceutical Sciences, Osaka University

• AKAI Shuji

  Faculty of Pharmaceutical Sciences, Osaka University

• Kita Yasuyuki

  Faculty Of Pharmaceutical Sciences Osaka University

• Kawaguchi Ken-ichi

  Faculty Of Pharmaceutical Sciences Osaka University

• Iio Kiyosei

  Faculty Of Pharmaceutical Sciences Osaka University

• Okuno T

  Faculty Of Pharmaceutical Sciences Osaka University

• Takeda Y

  Faculty Of Pharmaceutical Sciences Osaka University

• Takeda Yoshifumi

  Faculty Of Pharmaceutical Sciences Tokyo University Of Science (rikadai)

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