BENZYLIDENECYANOMETHYL-1,3-BENZAZOLES AS 1-AZA-1,3-BUTADIENES

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概要

• 論文の詳細を見る

• Diels-Alder reactions of benzylidenecyanomethyl-1,3-benzothiazoles and -1,3-benzoxazoles 2a-f as 1-aza-1,3-butadienes are described. The dienes 2,featuring the stabilized imine moieties by constituting heteroaromatic rings, react with both electron-deficient and electron-rich dienophiles 3a-c to give corresponding cycloadducts 4-6,regioselectively. The cycloadditions of the intramolecular systems 8a-d smoothly undergo via exo-transition state, stereoselectively affording polycyclic compounds 9a-d in good to excellent yields.

• 公益社団法人日本薬学会の論文
• 1994-06-15

著者

• 岡村 公生

  Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.,

• 伊達 忠正

  Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.,

• 坂本 正徳

  Meiji College of Pharmacy

• 坂本 正徳

  明治薬科大学

• Suzuki Y

  Fukuoka Inst. Technol. Fukuoka

• 長野 真弓

  Meiji College Of Pharmacy

• 鈴木 陽子

  Meiji College Of Pharmacy

• Suzuki Y

  Core Research For Evolutional Science And Technology (crest Jst) University Of Shizuoka School Of Ph

• 田村 修

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Tamura Osamu

  Meiji College Of Pharmacy

• 岡村 公生

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• 田村 修

  Meiji College of Pharmacy

• 野阪 麻江

  Meiji College of Pharmacy

• 島本 美乃

  Meiji College of Pharmacy

• 尾崎 秀樹

  Meiji College of Pharmacy

• 吉岡 早苗

  Meiji College of Pharmacy

• Sakamoto M

  Meiji College Of Pharmacy

• 伊達 忠正

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• Nagano M

  Kyoritsu College Of Pharmacy

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