Clarithromycin Inhibits Progeny Virus Production from Human Influenza Virus-Infected Host Cells(Microbiology)
スポンサーリンク
概要
- 論文の詳細を見る
In vitro effects of macrolide clarithromycin (CAM) on influenza A virus-infected cells were examined using plaque reduction assay by treating cells either before or after viral adsorption. The significant inhibitory effect on influenza virus infection was detected only when the cells were treated with CAM after viral adsorption. The predominant inhibitory effect was observed during 4-7th hour after viral adsorption using viral production assay. CAM did not exhibit inhibitory effects on influenza virus hemagglutination, membrane fusion and viral sialidase activities. These findings indicate that CAM acts on a middle to late stage of the viral replication cycle resulting in inhibition of progeny virus production from the infected cells.
- 社団法人日本薬学会の論文
- 2008-02-01
著者
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HIDARI Kazuya
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research
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TAKAHASHI Tadanobu
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research
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SAKANO Yuichi
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research
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SUZUKI Takashi
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research
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MIYAMOTO Daisei
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research
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Suzuki Y
School Of Pharmaceutical Sciences University Of Shizuoka
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Hidari Kazuya
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:core Research Fo
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Hidari Kazuya
宮武内科
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Hidari Kazuya
静岡県立大学 薬学部生体分子薬学分野
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Hidari Kazuya
Department Of Biochemical Cell Research The Tokyo Metropolitan Institute Of Medical Science
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Suzuki Y
Fukuoka Inst. Technol. Fukuoka
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YINGSAKMONGKON Sangchai
Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University
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SRIWILAIJAROEN Nongluk
Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University
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GUO Chao-Tan
Core Research for Evolutional Science and Technology, Japan Science and Technology Agency
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HASEGAWA Sayaka
Department of Biochemistry, University of Shizuoka School of Pharmaceutical Sciences
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HIRAMATSU Hiroaki
Core Research for Evolutional Science and Technology (CREST, JST), University of Shizuoka School of
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SUZUKI Yasuo
Core Research for Evolutional Science and Technology (CREST, JST), University of Shizuoka School of
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Hidari Kazuya
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:core Research Fo
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Hidari Kazuya
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences
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鈴木 陽子
Meiji College Of Pharmacy
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Suzuki T
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:core Research Fo
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Suzuki Y
Department Of Pharmacobiology And Therapeutics Faculty Of Pharmacy Meijo University
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Suzuki Y
Core Research For Evolutional Science And Technology (crest Jst) University Of Shizuoka School Of Ph
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Guo C‐t
Core Research For Evolutional Science And Technology (crest Jst) University Of Shizuoka School Of Ph
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Guo Chao-tan
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences
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Guo Chao-tan
Core Research For Evolutional Science And Technology (crest Jst) University Of Shizuoka School Of Ph
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Yingsakmongkon Sangchai
Department Of Biomedical Sciences College Of Life And Health Sciences Chubu University:department Of
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Sakano Yuichi
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:the Japan Health
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Sriwilaijaroen Nongluk
Department Of Biomedical Sciences College Of Life And Health Sciences Chubu University:graduate Stud
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Takahashi N
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:core Research Fo
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Hiramatsu Hiroaki
Core Research For Evolutional Science And Technology (crest Jst) University Of Shizuoka School Of Ph
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Hasegawa Sayaka
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:global Coe Progr
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Miyamoto Daisei
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:core Research Fo
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Suzuki Yasuo
Core Research For Evolutional Science And Technology (crest Jst) University Of Shizuoka School Of Ph
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Suzuki Y
Grad. Sch. Bioagric. Sci. Nagoya Univ.
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Suganuma Taiyo
(pressent Address)department Of Pharmacology Tokyo Women's Medical University
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Suzuki Takashi
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:core Research Fo
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Takahashi Tadanobu
Department Of Biochemistry School Of Pharmaceutical Sciences University Of Shizuoka And Global Coe P
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Suzuki Y
Department Of Pharmacology Faculty Of Pharmacy Meijo University
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Suzuki Takashi
Department Of Anesthesia Showa University Northern Yokohama Hospital
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Hidari Kazuya
Univ. Shizuoka Shizuoka
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Suzuki Takashi
Department Of Anatomic Pathology Tohoku University School Of Medicine
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