Synthetic Studies for Novel Structure of α-Nitrogenously Functionalized α-Fluorocarboxylic Acids. II. Synthesis and Some Reactions of α-Fluoro-α-nitrocarboxylic Ester and Carboxamide Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
The first synthesis of α-fluoro-α-nitrocarboxamides 11b, c has been achieved by ammonolysis of the corresponding ethyl esters 6b, c. However, α-fluoro-α-nitrocarboxylic acids 8a-c derived from the corresponding esters 6a-c were found to decarboxylate readily to form 1-fluoro-1-nitroalkanes 9a-c. Reduction of the α-fluoro-α-nitrocarboxamide derivatives 11b, c produced the defluorination products 12b, c instead of the desired novel α-fluoro-α-aminocarboxamide 2.
- 社団法人日本薬学会の論文
- 1991-12-25
著者
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小泉 徹
富山医科薬科大学薬学部薬化学
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小泉 徹
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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竹内 義雄
富山大院医薬
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竹内 義雄
Faculty Of Pharmaceutical Sciences University Of Tokyo
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Koizumi T
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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高木 久美子
Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutical University
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永田 和弘
Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutical University
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Nagata K
School Of Pharmaceutical Sciences Showa University
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小泉 徹
Department Of Synthetic Organic Chemistry:faculty Of Pharmaceutical Sciences Toyama Medical And Phar
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Koizumi Toru
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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高木 久美子
Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University
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永田 和弘
School Of Pharmaceutical Sciences Showa University
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