Synthesis and Optical Resolution of 4,6-Dideoxy-3,5-O-isopropylidene-2-O-(methoxymethyl)-DL-glucitol
スポンサーリンク
概要
- 論文の詳細を見る
4,6-Dideoxy-3,5-O-isopropylidene-2-O-(methoxymethyl)-DL-glucitol (3) was conveniently prepared from (±)-parasorbic acid (4). Resolution of the racemate 3 into the D-and L-isomers, each of which serves as a synthetic building block for the sugar moiety of naturally occurring (-)-griseusin A (2) or its enantiomer (1), was effected by high-performance liquid chromatography of its benzoate (12) on a column packed with (+)-poly (triphenylmethylmethacrylate) on macroporous silica gel [Chiralpak OT (+)^[O!R]].
- 社団法人日本薬学会の論文
- 1983-11-25
著者
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竹内 義雄
富山大院医薬
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竹内 義雄
Faculty Of Pharmaceutical Sciences University Of Tokyo
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吉井 英一
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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吉井 英一
富山医科薬科大学薬学部
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古村 睦美
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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古村 睦美
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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