Oxidation of Sulfides and Epoxidation of Olefins Caused by the Reaction of Pd-Peroxo or Co-Superoxo Complex with Carboxylic Acid Derivatives

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概要

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• The Pd-peroxo complex (dioxygen)bis(triphenylphosphine)palladium [Pd(Ph_3P)_2O_2] caused epoxidation of olefins and oxidations of sulfides and sulfoxides in the presence of carboxylic acid derivatives. The Co-superoxo complex cobalt bis (salicylaldehyde)-3,3'-diamino-di-n-propylamine [Co(Salpr)O_2] also oxidized sulfides to sulfoxides during the reaction with carboxylic acid derivatives. These oxidations were dependent upon the presence of a metal-dioxygen complex and an electrophile such as acyl cation. Metal-acylperoxide, generated in situ by the reaction of metal-dioxygen complex with a carboxylic acid derivative, could promote heterolytic cleavage of the O-O bond of dioxygen coordinated to metal to form a metal-oxo complex, which seems to be the ultimate species mediating the oxidations.

• 公益社団法人日本薬学会の論文
• 1988-06-25

著者

• 長野 哲雄

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 広部 雅昭

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 増野 匡彦

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 広部 雅昭

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 広部 雅昭

  東京大学薬学部:文部省

• 増野 匡彦

  Faculty Of Pharmaceutical Sciences University Of Tokyo

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