Studies on Peptides. LXXXII. Synthesis of [4-Gln]-Neurotensin by the Methanesulfonic Acid Deprotecting Procedure
スポンサーリンク
概要
- 論文の詳細を見る
In order to examine the side reaction at the tyrosine residue, i.e., O-sulfonation, that occurs during the methanesulfonic acid deprotection of Arg (p-methoxybenzenesulfonyl), [4-Gln]-neurotensin was synthesized as a model peptide. A mixture of cation scavengers, anisole-thioanisole-o-cresol (1 : 1 : 1), suppressed this side reaction sufficiently for practical peptide synthesis.
- 社団法人日本薬学会の論文
- 1979-09-25
著者
-
安達 秀樹
School of Medicine, Kyoto University
-
安達 秀樹
University Hospital Faculty Of Medicine Kyoto University
-
大石 まり子
国立京都病院内分泌代謝疾患センター
-
大石 まり子
国立京都病院
-
赤澤 好温
国立京都病院糖尿病センター臨床研究部
-
斉藤 均
Faculty of Pharmaceutical Sciences
-
赤澤 好温
National Kyoto Hospital
-
赤路 健一
Faculty Of Pharmaceutical Sciences Kyoto University
関連論文
- 3.原発性肺平滑筋肉腫の1例 : 第23回肺癌学会関関西支部会
- Studies on Peptides. LXIV. Synthesis of the Tritetracontapeptide corresponding to the Entire Amino Acid Sequence of Porcine Gastric Inhibitory Polypeptide (GIP)
- 多彩イな臨床症状を伴ったミトコンドリア遺伝子異常
- 糖尿病の医療経済 (1月第5土曜特集--糖尿病--病態の解明と治療の最前線) -- (糖尿病の治療)
- 医療経済的にみた糖尿病診療とは (特集 糖尿病診療Step2--ドロップアウトさせないために) -- (総論)
- ICA, 抗 GAD 抗体陽性のインスリン依存型糖尿病を発症した Charcot-Marie-Tooth 病の 1 例
- I-A-11 四逆散と芍薬甘草湯の消化管運動に及ぼす影響
- I-A-10 各種漢方方剤の消化管運動に及ぼす影響
- I-A-9 薬物の消化管運動に及ぼす影響を定量的に測定するための方法の開発と方剤への応用
- Studies on Peptides. CXXXVI. : Solution-Phase Synthesis of a 37-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Human Calcitonin Gene-Related Peptide (hCGRP)
- Studies on Peptides. CXLI. : Synthesis of a 42-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Porcine GIP (Glucose-Dependent Insulinotropic Polypeptide)
- Studies on Peptides. CXXXIX. : Solution Synthesis of a 42-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Human Glucose-Dependent Insulinotropic Polypeptide (GIP)
- Studies on Peptides. CXXXIII. : Synthesis and Biological Activity of Galanin, a Novel Porcine Intestinal Polypeptide
- SYNTHESIS OF A 42 RESIDUE PEPTIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN GIP
- 78) 放射性物質で標識した生薬の調製と, その和漢医薬学研究への応用
- 糖尿病外来医療費に関する研究
- Synthesis of [27-Tyr]-Cholecystokinin-Pancreozymin (CCK-PZ)
- 62. 妊娠と糖尿病について(第3報)
- Studies on Peptides. CXLVI. : Synthesis of Gln^-Motilin and Examination of Its Immunological Properites
- Studies on Peptides. CXLV. : Synthesis of a 27-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Canine Gastrin-Releasing Polypeptide (cGRP)
- Studies on Peptides. CXL. : Synthesis of Human Gastrin-Releasing Polypeptide (hGRP)
- SYNTHESIS OF A 27-RESIDUE PEPTIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN GASTRIN-RELEASING PEPTIDE (hGRP)
- 69) 糖尿病患者の振動感覚低下に対する八味地黄丸薬効の定量的評価
- Studies on Peptides. CV. Synthesis of Chicken Neurotensin
- Studies on Peptides. LXXXII. Synthesis of [4-Gln]-Neurotensin by the Methanesulfonic Acid Deprotecting Procedure
- MCインスリンの奏功したインスリンアレルギ-の2症例
- Studies on Peptides. CLI. Syntheses of Cystine-Peptides by Oxidation of S-Protected Cysteine-Peptides with Thallium(III) Trifluoroacetate(Organic,Chemical)
- Studies on Peptides. CXLIII. : Evaluation of β-Methylaspartate for Peptide Synthesis
- Synthesis of a Heptacosapeptide Amide corresponding to the Entire Amino Acid Sequence of Chicken Gastrin Releasing Peptide (GRP)
- Synthesis of a Heptacosapeptide Amide corresponding to the Entire Amino Acid Sequence of Gastric Gastrin Releasing Peptide
- Studies on Peptides. LXVIII. Synthesis of the Tritriacontapeptide Amide corresponding to the Entire Amino Acid Sequence of the Desulfated Form of Porcine Cholecystokinin-Pancreozymin (CCK-PZ)
- Studies on Peptides. CLVII. : Synthesis of a Frog-Skin Peptide, Sauvagine
- Studies on Peptides. CXXXII. : Evaluation of Two β-Carboxyl Protecting Groups of Aspartic Acid, Cycloheptyl and Cyclooctyl, for Peptide Synthesis
- Studies on Peptides. CXXXV. : Preparation of Seven Peptide Fragments for the Synthesis of Human Calcitonin Gene-Related Peptide (hCGRP)
- Studies on Peptides. CXXIV. Solution Synthesis of the Hentetracontapeptide Amide Corresponding to the Entire Amino Acid Sequence of Human Corticotropin Releasing Factor (hCRF)
- Studies on Peptides. CXXIII. Preparations of Nine Peptide Fragments for the Synthesis of Human Corticotropin Releasing Factor (hCRF)
- SYNTHESIS OF A HENTETRACONTAPEPTIDE AMIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN CORTICOTROPIN RELEASING FACTOR (hCRF)
- SOLUTION SYNTHESIS OF A TETRATETRACONTAPEPTIDE AMIDE WITH GROWTH HORMONE RELEASING ACTIVITY
- II-C-11 三黄瀉心湯経口投与後の血清による培養肝細胞アセチル CoA カルボキシラーゼの抑制
- Solution Synthesis of a Heptacosapeptide known as Bovine γ_3-Melanotropin (γ_3-MSH)
- Studies on Peptides. CLX. : Synthesis of a 33-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Human Cholecystokinin (hCCK-33)
- Studies on Peptides. CLXVIII. : Syntheses of Three Peptides Isolated from Horseshoe Crab Hemocytes, Tachyplesin I, Tachyplesin II, and Polyphemusin I
- Studies on Peptides. CLXVII. / Solid-Phase Syntheses and Immunological Properties of Fragment Peptides Related to Human Malaria Circumsporozoite Protein
- Studies on Peptides. CLIX. : Preparation of a Protected 33-Residue Peptide for the Synthesis of Human Cholecystokinin (hCCK-33)
- Studies on Peptides. XCV. Alternative Synthesis of Porcine Vasoactive Intestinal Polypeptide (VIP)
- Synthesis of an Octacosapeptide Amide corresponding to the Entire Amino Acid Sequence of Chicken Vasoactive Intestinal Polypeptide (VIP)
- Studies on Peptides. CXXIX. Application of N^-Mesitylenesulfonyl-tryptophan for the Syntheses of Neuromedin B and Neuromedin C
- 上皮細胞増殖因子の活性を持つペプチドの合成
- Studies on Peptides. CXXVII. Synthesis of a Tripentacontapeptide with Epidermal Growth Factor Activity
- Studies on Peptides. CXLVII. Synthesis of Valosin, a Novel 25-Residue Peptide from Porcine Intestine(Organic,Chemical)
- Studies on Peptides CXLIV. : Synthesis and Immunological Properties of Formylmethionyl Human Adrenocorticotropin
- イヌ胃体部粘膜におけるガストリンの作用機序に関する研究-2-Ca2+-activated,phospholipid-dependent protein kinase活性とリン脂質代謝におよぼすガストリンの影響
- イヌ胃体部粘膜におけるガストリンの作用機序に関する研究-1-Adenylate cyclase活性の検討
- Studies on Peptides. CXV. Synthesis of Hylambatin, a New Frog Skin Peptide of the Kassinin Family
- Studies on Peptides. CXVI. Synthesis of the Protected Docosapeptide Corresponding to the C-Terminal Portion of Human Growth Hormone Releasing Factor (GRF, Somatocrinin)
- Studies on Peptides. XCVI. Behavior of S-Acetamidomethylcysteine Sulfoxide under Deprotecting Conditions in Peptide Synthesis
- Studies on Peptides. CXXII. N-Succinimidyl-p-(2-nitrovinyl)-benzoate and Its m-Isomer, as Heterobifunctional Conjugating Reagents for Immunoassay
- 放射線食道炎及び直腸炎に対するアルギン酸ナトリウムの臨床効果
- II-B-2 潰瘍性大腸炎を合併した神経性食思不振症の一例(摂食障害VIII)
- Studies on Peptides. CXLIX. : Solid-Phase Synthesis of a Rabbit Stomach Peptide by Application of a New Polymer Support and a New Deprotecting Procedure(Organic,Chemical)
- Studies on Peptides. CVII. Synthesis of Urotensin II
- Studies on Peptides. CXXV. 3-(3-p-Methoxybenzylthiopropionyl)-thiazolidine-2-thione and Its Analogs as Reagents for the Introduction of the Mercapto Group into Peptides and Proteins
- Studies on Peptides. CXXVI. Synthesis of the Protected Tetracosapeptide Corresponding to Positions 30-53 of Mouse Epidermal Growth Factor (EGF)
- Studies on Peptides. XCIV. Thiazoline-2-thione as a Carboxyl-activating Reagent for Petide Synthesis
- 1.疫学の立場から