Further Preparation of Steroidal Diosphenols. I. Synthesis of Some 4,4-Dimethyl-2-hydroxy-3-oxo-1-ene Steroids in Androstane and Pregnane Series
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概要
- 論文の詳細を見る
Some 2-hydroxy-3-oxo-4,4-dimethyl-1-ene steroids and two 4-hydroxy-3-oxo-2,2-dimethyl-4-ene steroids were prepared in order to obtain anti-tumor substances against sex hormone dependent cancer such as breast cancer and prostatic cancer. These diosphenols were synthesized by the autoxidation of the corresponding 3-oxo steroids in the presence of potassium tert-butoxide in tert-butanol.
- 社団法人日本薬学会の論文
- 1968-09-25
著者
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森 弘
Chemical Research Department Teikoku Hormone Mfg. Co. Ltd.
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常田 清
Research Laboratory, Teikoku Hormone Mfg. Co., Ltd.
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和田 俊洋
Research Laboratory, Teikoku Hormone Mfg. Co., Ltd.
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高谷 治
National Cancer Center Hospital
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柴田 健雄
Research Department Teikoku Hormone Mfg. Co. Ltd.
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安田 喜久男
Research Division Teikoku Hormone Manufacturing Co. Ltd.
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常田 清
Research Laboratory Teikoku Hormone Mfg. Co. Ltd.
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和田 俊洋
Research Laboratory Teikoku Hormone Mfg. Co. Ltd.
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