Synthesis of Ecdysone. III. A Novel Synthesis of 14α-Hydroxy-7-en-6-oxo Steroids
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概要
- 論文の詳細を見る
A novel synthetic method of 14α-hydroxy-6-oxo-7-ene steroid from 6-oxo-7-ene steroid was developed. The enol acetylation of 7-en-6-one with acetic anhydride in the presence of perchloric acid afforded 6-acetoxy-6,8 (14)-diene, which on treatment with monoperphthalic acid gave 14α-hydroxy-7-en-6-one. 2β, 3β, 14α-Trihydroxy-5β-cholest-7-en-6-one (XXVIII), the nuclear structure of which is the same as that of ecdysone, was prepared by this method, and the stereochemistry of XXVIII and related compounds was studied.
- 社団法人日本薬学会の論文
- 1968-08-25
著者
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柴田 承二
Shibata Laboratory of Natural Medicinal Materials
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沢井 政信
Research Laboratory Teikoku Hormone Mfg. Co. Ltd.
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森 弘
Chemical Research Department Teikoku Hormone Mfg. Co. Ltd.
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森 弘
Research Laboratory, Teikoku Hormone Mfg. Co., Ltd., Shimosakunobe, Kawasaki
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常田 清
Research Laboratory, Teikoku Hormone Mfg. Co., Ltd.
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柴田 承二
Research Laboratory, Teikoku Hormone Mfg., Co., Ltd.
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常田 清
Research Laboratory Teikoku Hormone Mfg. Co. Ltd.
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