Synthesis of Exdysone.I.A Novel Synthesis of 2β, 3β-Dihydroxy Steroids
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概要
- 論文の詳細を見る
A novel synthesis of 2β, 3β-dihydroxy steroids from 3-oxo compounds in 5α-series was developed. Autoxidation of 3-oxo compound afforded an enol mixture of 2,3-dioxo compound, which on reduction with sodium borohydride yielded 2β, 3β-dihydroxy steroid. It was found that 2β, 3β-dihydroxy steroid was obtained with high stereospecificity by the reduction of 2-hydroxy-1-en-3-oxo steroid.
- 社団法人日本薬学会の論文
- 1967-04-25
著者
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沢井 政信
Research Laboratory Teikoku Hormone Mfg. Co. Ltd.
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森 弘
Chemical Research Department Teikoku Hormone Mfg. Co. Ltd.
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柴田 健雄
Research Laboratory, Teikoku Hormone Mfg. Co., Ltd.
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森 弘
Research Laboratory, Teikoku Hormone Mfg. Co., Ltd., Shimosakunobe, Kawasaki
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常田 清
Research Laboratory, Teikoku Hormone Mfg. Co., Ltd.
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柴田 健雄
Research Department Teikoku Hormone Mfg. Co. Ltd.
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常田 清
Research Laboratory Teikoku Hormone Mfg. Co. Ltd.
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