An Isotope Effect on the Comparative Quantification of Flavonoids by Means of Methylation-Based Stable Isotope Dilution Coupled with Capillary Liquid Chromatography/Mass Spectrometry(Methods)
スポンサーリンク
概要
- 論文の詳細を見る
Ionization suppression is a serious problem in liquid chromatography/mass spectrometry-based metabolomics, and stable isotope dilution-based comparative quantification is one of the most important methods of overcoming this problem. Herein, the use of [^<13>C]-methylation-based stable isotope dilution for comparative quantification of flavonoids is demonstrated. This is in contrast to the equivalent deuterium labeling methylation method, which has an adverse isotope effect on reverse phase chromatography.
- 社団法人日本生物工学会の論文
- 2005-01-25
著者
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Bamba Takeshi
Department of Biotechnology, Graduate School of Engineering, Osaka University
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Harada Kazuo
Department Of Biotechnology Graduate School Of Engineering Osaka University:(present Office)departme
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KOBAYASHI AKIO
Department of Biotechnology, Graduate School of Engineering, Osaka University
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KAWABE Akira
Department of Biotechnology, Graduate School of Engineering, Osaka University
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Kobayashi A
National Inst. Advanced Industrial Sci. And Technol. Ibaraki Jpn
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Bamba Takeshi
Department Of Applied Environmental Biology Graduate School Of Pharmaceutical Sciences Osaka Univers
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Kobayashi A
Laboratory Of Bioresources Chemistry Faculty Of Agriculture Okayama University
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Harada Kazuo
Applied Environmental Biology Graduate School Of Pharmaceutical Sciences Osaka University
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Kobayashi A
Dep. Of Biotechnology Graduate School Of Engineering Osaka Univ.
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Bamba Takeshi
Dep. Of Biotechnology Graduate School Of Engineering Osaka Univ. 2- 1 Yamadaoka Suita Osaka 565-0871
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Bamba Takeshi
Dept. Biotech. Grad. Sch. Eng. Osaka Univ.:hitachi Zosen Co.
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Fukusaki Eiichiro
Division Of Advanced Science And Biotechnology Graduate School Of Engineering Osaka University
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Fukusaki Eiichiro
Dep. Of Biotechnology Graduate School Of Engineering Osaka Univ.
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Fukusaki Ei-ichiro
大阪大学大学院
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Hirata Kazumasa
Dep. Of Applied Environmental Biology Graduate School Of Pharmaceutical Sciences Osaka Univ.
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Fukusaki E
Department Of Biotechnology Graduate School Of Engineering Osaka University
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Harada Kazuo
Department Of Applied Environmental Biology Graduate School Of Pharmaceutical Sciences Osaka Univers
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Kobayashi Akio
Department Of Biotechnology Graduate School Of Engineering Osaka University
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KOBAYASHI Akio
Department of Biochemistry, Shinshu University School of Medicine
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KOBAYASHI Akio
Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku University
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