Kojic Acid Production in an Airlift Bioreactor Using Partially Hydrolyzed Raw Corn Starch

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概要

• 論文の詳細を見る

• In a culture of Aspergillus oryzae MK-107-39 in a 3-l airlift bioreactor, kojic acid was not produced when glucose/wheat germ medium (GM1) was used. However, when a jar fermentor was used, the kojic acid yield was high. A suitable medium for culture in an airlift bioreactor consisting of partially hydrolyzed corn starch and a small amount of corn steep liquor (CSL)(SM1) was selected. In the cultivation in the airlift bioreactor using SM1, nearly 40 g/l or kojic acid was produced, which was the same as the amount produced in the jar fermentor containing GM1. The optimum aeration rate for the airlift bioreactor was 2.0 vvm (0.66 cm/s of superficial linear velocity (Vs)). The cost of SM1 using the airlift bioreactor was reduced to 40% that of GM1 using the jar fermentor. Furthermore, the energy cost of kojic acid production using SM1 in the airlift bioreactor was less than one-fourth of that for the jae fermentor using GM1.

• 社団法人日本生物工学会の論文
• 2001-10-25

著者

• HUANG GUOWEI

  United Graduate School of Agricultural Science, Gifu University

• Tamura Tomohiko

  Nite Biological Resource Center (nbrc) National Institute Of Technology And Evaluation

• Okabe Mitsuyasu

  Mercian Co. Central Research Laboratories

• Okabe Mitsuyasu

  Biotechnology Lab. Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka Univer

• Okabe Mitsuyasu

  Laboratory Of Biotechnology Faculty Of Agriculture Shizuoka University

• Okabe Mitsuyasu

  Biochemical Engineering Laboratory Department Of Applied Biological Chemistry Faculty Of Agriculture

• Okabe Mitsuyasu

  (present Address)department Of Applied Biochemistry Faculty Of Agriculture Shizuoka University

• Ishihara Hironori

  Biotechnology Lab. Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka Univer

• Huang Guowei

  United Graduate School Of Agricultural Science Gifu University

• FUTAMURA TAKAFUMI

  United Graduate School of Agricultural Science, Gifu University

• TAMURA TAKAYOSHI

  Pharmaceutical Technology Laboratories, Meiji Seika Ltd.,

• YASUTAKE TETSUYA

  Pharmaceutical Technology Laboratories, Meiji Seika Ltd.,

• KOJIMA MAMI

  United Graduate School of Agricultural Science, Gifu University

• Kojima Mami

  United Graduate School Of Agricultural Science Gifu University

• Okabe M

  Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University

• Futamura Takafumi

  United Graduate School Of Agricultural Science Gifu University

• Yasutake Tetsuya

  Pharmaceutical Technology Laboratories Meiji Seika Ltd.

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