Protective effects of intranasal vaccination with plasmid encoding pseudorabies virus glycoprotein B in mice
スポンサーリンク
概要
- 論文の詳細を見る
Intranasal administration of plasmid DNA encoding glycoprotein B of pseudorabies virus into mice induced both serum and secretory antibody responses. These mice resisted intranasal challenge with lethal dose of the virus, but did not intraperitoneal challenge. On the other hand, intramuscular injection of the plasmid induced less secretory and higher serum antibody responses than those of intranasally vaccinated mice. None of them was protected from virus challenge. The present results suggest that administration of plasmid DNA encoding glycoprotein B by respiratory mucosal route generates local secretory antibodies which serve to protect animals from pseudorabies virus infection.
- 北海道大学の論文
- 1999-08-31
著者
-
Takada Ayato
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
-
OKAZAKI Katsunori
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, H
-
KIDA Hiroshi
Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
-
Okazaki Katsunori
Department Of Disease Control Graduate School Of Veterinary Medicine Hokkaido University
-
Okazaki Katsunori
北海道大学 獣医研究 動物疾病制御
-
Otsuki K
Tottori Univ. Tottori Jpn
-
Kida Hiroshi
東京大 海洋研 大槌臨海研究セ
-
高田 礼人
北海道大学人獣共通感染症リサーチセンター
-
Kida Hiroshi
Hokkaido Univ. Hokkaido Jpn
-
Kida Hiroshi
Department Of Cardiology Kanazawa National Hospital
-
Kida Hiroshi
Department Of Disease Control Graduate School Of Veterinary Medicine Hokkkaido University
-
Okazaki Katsunori
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
-
Takada Ayato
Laboratory Of Microbiology
-
Kida Hiroshi
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
-
Kida Hiroshi
Department Of Disease Control Graduate School Of Veterinary Medicine Hokkaido University
-
Okazaki Katsunori
Laboratory Of Microbiology And Immunology Faculty Of Pharmaceutical Sciences Health Sciences Univers
関連論文
- Increase in the Neuraminidase Activity of a Nonpathogenic Newcastle Disease Virus Isolate during Passaging in Chickens
- インフルエンザウイルスの抗原変異予測とワクチン (特集 新型インフルエンザウイルス)
- Characterization of H5N1 Highly Pathogenic Avian Influenza Virus Isolated from a Mountain Hawk Eagle in Japan
- C-type lectins do not act as functional receptors for filovirus entry into cells
- インフルエンザウイルスの進化における共変異の変化の解析(セッション7)
- Predicting the Antigenic Structure of the Pandemic (H1N1) 2009 Influenza Virus Hemagglutinin
- Disease constraints for utilization of the African buffalo (Syncerus caffer) on game ranches in Zambia
- Viral and bacterial diseases in livestock in Mongolia
- Protective effects of intranasal vaccination with plasmid encoding pseudorabies virus glycoprotein B in mice
- Antigenic and genetic analyses of H5 influenza viruses isolated from ducks in Asia
- Laboratory of Microbiology
- Hierarchy among viral RNA (vRNA) segments in their role in vRNA incorporation into influenza A virions
- Highly Pathogenic H5N1 Influenza Virus Causes Coagulopathy in Chickens
- Ebola virus VP40 drives the formation of virus-like filamentous particles along with GP
- Immunogenicity and Protective Efficacy of Replication-Incompetent Influenza Virus-Like Particles
- Infectivity-Enhancing Antibodies to Ebola Virus Glycoprotein
- Mucosal vaccination against influenza : Protection of pigs immunized with inactivated virus and ether-split vaccine
- Functional Importance of the Coiled-Coil of the Ebola Virus Glycoprotein
- Recognition of N-Glycolylneuraminic Acid Linked to Galactose by the α2,3 Linkage Is Associated with Intestinal Replication of Influenza A Virus in Ducks
- Avirulent Avian Influenza Virus as a Vaccine Strain against a Potential Human Pandemic
- 自然界の馬1型および馬2型インフルエンザウイルスの遺伝子進化におけるマトリックス蛋白以外の内部蛋白遺伝子置換
- 鶏および水禽由来ニューカッスル病ウイルスの間のレセプター特異性の相違
- Molecular Basis for the Generation in Pigs of Influenza A Viruses with Pandemic Potential
- Potentially virulent Newcastle disease viruses are maintained in migratory waterfowl populations
- ACQUISITION OF PATHOGENICITY OF A NEWCASTLE DISEASE VIRUS ISOLATED FROM A JAPANESE QUAIL BY INTRACEREBRAL PASSAGE IN CHICKENS
- Ecology and epidemiology of anthrax in cattle and humans in Zambia
- Characterization of H3N6 avian influenza virus isolated from a wild white pelican in Zambia
- フィロウイルスと細胞膜
- フィロウイルスの細胞への侵入 (特集 ウイルス増殖に関わる宿主細胞分子)
- 鼎談 これからのインフルエンザワクチン
- A vaccine prepared from a non-pathogenic H5N1 influenza virus strain from the influenza virus library conferred protective immunity to chickens against the challenge with antigenically drifted highly pathogenic avian influenza virus
- A serological survey of minute virus of canines (MVC ; Canine parvovirus type-1) in dogs in the Tokai area of Japan
- A Low Pathogenic H5N2 Influenza Virus Isolated in Taiwan Acquired High Pathogenicity by Consecutive Passages in Chickens
- Detection of all known filovirus species by reverse transcription-polymerase chain reaction using a primer set specific for the viral nucleoprotein gene
- Cardiac Sympathetic Nervous System Represses Natriuretic Peptide Release in Humans
- Relationship between plasma homocysteine and coronary stenosis morphology in Japanese patients with coronary artery disease
- Effects of Endoscopic Transthoracic Sympathicotomy on Hemodynamic and Neurohumoral Responses to Exercise in Humans
- Influenza A Virus Can Undergo Multiple Cycles of Replication without M2 Ion Channel Activity
- Antibodies to Human-Related H3 Influenza A Virus in Baikal Seals (Phoca sibirica) and Ringed Seals (Phoca hispida) in Russia
- Influenza virus infection in seal (Phocidae) : seroepidemiological survey of influenza virus in Caspian seals(Phoca caspica)
- Serological Evidence of Transmission of Human Influenza A and B Viruses to Caspian Seals (Phoca caspica)
- OJ-204 The Course Taken by Sympathetic Efferent Fibers from Th4 Ganglion to The Sinus Node in Humans(Autonomic Nervous System 2 (H) : OJ23)(Oral Presentation (Japanese))
- Prevalence of Migraine and Raynaud's Phenomenon in Japanese Patients With Vasospastic Angina
- Cioning, Tissue Distribution, and Functional Expression of Two Novel Rabbit Cytochrome P450 Isozymes, CYP2D23 and CYP2D24
- Electron-dense deposition patterns and the outcomes of idiopathic membranous nephropathy in Japanese
- DETECTION OF VIRAL GENOME IN NON-NEURAL TISSUES OF CATTLE EXPERIMENTALLY INFECTED WITH BOVINE HERPESVIRUS 1
- Subcutaneous Hematoma Due to Frequent Insulin Injections in a Single Site
- Effect of Endoscopic Transthoracic Sympathicotomy on Plasma Natriuretic Peptide Concentrations in Humans
- Development of an Immunochromatographic Kit for Rapid Diagnosis of H5 Avian Influenza Virus Infection
- Evaluation of the ESPLINE^【○!R】 INFLUENZA A&B-N Kit for the Diagnosis of Avian and Swine Influenza
- A Comparison of the Antibody Responses between Specific Pathogen-Free and Commercial Layers Immunized with an Influenza Vaccine Prepared from Inactivated Non-Pathogenic H5N1 Virus by Single Shot
- 海生哺乳動物由来インフルエンザAウイルスのレセプター特異性はその宿主の肺のシアル酸糖鎖と相関する
- VIRAL DISEASES OF LIVESTOCK IN ZAMBIA
- インフルエンザウイルスの進化における共変異の変化の解析(セッション7)
- Genetic Analyses of an H3N8 Influenza Virus Isolate, Causative Strain of the Outbreak of Equine Influenza at the Kanazawa Racecourse in Japan in 2007
- インフルエンザウイルスに対する免疫応答・感染防御機構 (特集 パンデミックインフルエンザ--最新の知見と今後の展望) -- (インフルエンザウイルス研究の進歩)
- エボラ出血熱 (特集 変貌する感染症--人類の備えは十分か?)
- フィロウイルスの病原性と宿主域 (ウイルス研究の現在と展望) -- (ウイルス病原性発現の分子機構)
- エンベロープウイルスの細胞侵入と粒子形成過程
- フィロウイルス感染症
- 北海道大学人獣共通感染症リサーチセンター国際疫学部門
- エボラウイルス表面糖蛋白質の機能解析
- ウイルスの病原性発現における糖タンパク質の役割 (免疫病と感染症)
- Enzyme-Linked Immunosorbent Assay for Detection of Filovirus Species-Specific Antibodies
- Effective Prevention against Rabies by Intracerebral Immunization in Mice
- BOVINE CLOSTRIDIAL INFECTIONS IN ZAMBIA (1985-1994)
- A NEUTRAL SUGAR IS RESPONSIBLE FOR SEROVAR SPECIFICITY OF THE ANTIGENIC DETERMINANT OF LEPTOSPIRA INTERROGANS SEROVAR CANICOLA
- SURVEY OF INFLUENZA VIRUSES IN FERAL BIRDS IN 1979 AND ISOLATION OF A STRAIN POSSESSING Hav6Nav5 FROM CLOACA OF AN EASTERN DUNLIN
- DISTRIBUTION OF ANTIBODIES IN ANIMALS AGAINST INFLUENZA B AND C VIRUSES
- Methylprednisolone Pulse Therapy in Two Clinical Types of Crescentic Glomerulonephritis
- Efficacy of Intracerebral Immunization against Pseudorabies Virus in Mice
- Possible circulation of H5N1 avian influenza viruses in healthy ducks on farms in northern Vietnam
- Isolation of Pseudomonas aeruginosa from Ushubetsu River water in Hokkaido, Japan
- Cleavage of the NS2-3 protein in the cells of cattle persistently infected with non-cytopathogenic bovine viral diarrhea virus
- Genetic and Pathobiological Characterization of Bovine Viral Diarrhea Viruses Recently Isolated from Cattle in Japan
- A Rapid and Highly Sensitive Method for Diagnosis of Equine Influenza by Antigen Detection Using Immuno-PCR
- Antigenic Variation Among Equine H 3 N 8 Influenza Virus Hemagglutinins
- An H5N1 highly pathogenic avian influenza virus that invaded Japan through waterfowl migration
- THE EFFECTIVENESS OF TRYPSIN TREATMENT TO REMOVE SENDAI VIRUS ADHERING TO THE ZONA PELLUCIDA OF MOUSE PREIMPLANTATION EMBRYOS
- フィロウイルスの感染機構と宿主因子 (感染現象--その理解の深化から疾患制御への展望) -- (ウイルスと宿主の相互作用)
- Pseudorabies virus early protein 0 transactivates the viral gene promoters
- Mapping of a functional region conferring nuclear localization of pseudorabies virus immediate-early protein
- Extensive Accumulation of Influenza Virus NS1 Protein in the Nuclei Causes Effective Viral Growth in Vero Cells
- Effect of Sendai Virus Exposure on the Development of Frozen-Thawed Mouse Embryos
- Serological Evidence of Leptospiral Infection in Pig Populations in Different Districts in Japan
- MUTATION OF GROWTH OF LEPTOSPIRES IN SHENBERG'S MEDIUM
- An H9N2 Influenza Virus Vaccine Prepared from a Non-Pathogenic Isolate from a Migratory Duck Confers Protective Immunity in Mice against Challenge with an H9N2 Virus Isolated from a Girl in Hong Kong
- Molecular Characterization of the Hemagglutinin and Neuraminidase Genes of H5N1 Influenza A Viruses Isolated from Poultry in Vietnam from 2004 to 2005
- Full genomic amplification and subtyping of influenza A virus using a single set of universal primers
- STUDIES ON CULTURAL AND SEROLOGICAL PROPERTIES AND VIRULENCE OF LEPTOSPIRA
- いきものの不思議 ウイルスはどうやって生き延びているのか? : インフルエンザウイルスの存続様式と進化
- Development and evaluation of indirect enzyme-linked immunosorbent assay for a screening test to detect antibodies against classical swine fever virus
- Favorable response to crizotinib in three patients with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion-type oncogene-positive non-small cell lung cancer
- Recurrent allergic bronchopulmonary aspergillosis in a patient with rheumatoid arthritis treated with etanercept and tocilizumab
- Two cases of leptomeningeal metastases from lung adenocarcinoma which progressed during gefitinib therapy but responded to erlotinib
- Recovery of Leptospires from Miniature Pigs Experimentally Infected with Leptospira interrogans Serovar Manilae Strain UP-MMC under Immunosuppressive Conditions by Dexamethasone
- Drug-induced Thrombotic Thrombocytopenic Purpura Successfully Treated with Recombinant Human Soluble Thrombomodulin