DETECTION OF VIRAL GENOME IN NON-NEURAL TISSUES OF CATTLE EXPERIMENTALLY INFECTED WITH BOVINE HERPESVIRUS 1
スポンサーリンク
概要
- 論文の詳細を見る
To obtain further information on the latent infection with bovine herpesvirus 1 (BHV-1) in the natural host, we examined the nasal secretions and various tissues of experimentally infected calves using virus isolation, polymerase chain reaction (PCR), and immuno-PCR/antigen (Immuno-PCR/Ag) assays. In the nasal secretions, viral DNA was detected in samples with virus isolation titers of 10^<4.3> TCID_<50> or more by PCR. On the same samples, Immuno-PCR/Ag remained positive up to day 19 p.i. the last day of test. BHV-1 DNA was detected from the following tissues in all the calves at day 22 p.i. : trigeminal ganglia, ovaries, lungs, nasal and tracheal mucosae, spleen, prescapular and precrural lymph nodes, and peripheral blood leukocytes (PBL), but not skeletal muscles. Virus was not recovered from any of these tissues. The present findings suggest a possible role of leukocytes in BHV-1 latent infection.
- 北海道大学の論文
- 1996-12-18
著者
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MWEENE Aaron
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, H
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KIDA Hiroshi
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, H
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OKAZAKI Katsunori
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, H
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Okazaki Katsunori
Department Of Disease Control Graduate School Of Veterinary Medicine Hokkaido University
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Okazaki Katsunori
北海道大学 獣医研究 動物疾病制御
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Mweene Aaron
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
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Otsuki K
Tottori Univ. Tottori Jpn
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Okazaki Katsunori
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
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Kida Hiroshi
Laboratory Of Microbiology Department Of Disease Control Hokkaido University Graduate School Of Vete
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Kida Hiroshi
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
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Okazaki Katsunori
Laboratory Of Microbiology And Immunology Faculty Of Pharmaceutical Sciences Health Sciences Univers
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KIDA Hiroshi
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
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