A Comparison of the Antibody Responses between Specific Pathogen-Free and Commercial Layers Immunized with an Influenza Vaccine Prepared from Inactivated Non-Pathogenic H5N1 Virus by Single Shot
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概要
- 論文の詳細を見る
It is known that antibody responses in chickens against invading organisms or antigens are considerable different among their lines. Then an avian influenza vaccine was prepared from inactivated whole particles of the virus of non-pathogenic strain A/duck/Hokkaido/Vac-1/04 (H5N1) using an oil adjuvant containing anhydromannitol-octadecenoate-ether. The vaccine was injected intramuscularly into each 10 ten-week-old specific pathogen-free (SPF) white leghorn chickens and commercial layers of Julia and Boris-Brown to obtain the comparative data of antibody responses until 6 weeks after vaccination. Despite significant partially differences of antibody titer between both chicken lines, this study made it clear that the vaccine induced good and sufficient antibody response in both SPF and commercial layers.
著者
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Sakoda Yoshihiro
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
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Imamura Takashi
Division 2, Second Research Department, The Chemo-Sero-Therapeutic Research Institute
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Sasaki Takashi
Avian Biologics Department, Kyoto Biken Laboratories, Inc.
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KOKUMAI Norihide
Avian Biologics Department, Kyoto Biken Laboratories, Inc.
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OHGITANI Toshiaki
Avian Biologics Department, Kyoto Biken Laboratories, Inc.
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LIN Zhifeng
Research Department, Nippon Institute for Biological Science
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Kida Hiroshi
Laboratory Of Microbiology Department Of Disease Control Hokkaido University Graduate School Of Vete
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SAWATA Akira
Research Center for Biologicals, The Kitasato Institute
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Kida Hiroshi
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
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