Recovery of Leptospires from Miniature Pigs Experimentally Infected with Leptospira interrogans Serovar Manilae Strain UP-MMC under Immunosuppressive Conditions by Dexamethasone
スポンサーリンク
概要
- 論文の詳細を見る
Leptospira interrogans serovar Manilae strain UP-MMC was inoculated into miniature pigs to assess its pathogenicity. Leptospires were recovered from the whole blood, kidneys, and livers in the acute phase without showing any clinical signs. Under immunosuppressive conditions by dexamethasone, leptospires were recovered from the kidneys and their genes were detected from the urine in the chronic phase. These results indicate that leptospires persisted in the kidneys until the chronic phase, and excretion of leptospires in the urine was enhanced under immunosuppressive conditions, resulting in horizontal transmission among pigs on farms.
- 日本獣医学会の論文
著者
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Sakoda Yoshihiro
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
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Tanaka Tomohisa
Laboratory Of Comparative Pathology Graduate School Of Veterinary Medicine Hokkaido University
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Umemura Takashi
Laboratory Of Comparative Pathology Department Of Veterinary Clinical Sciences Graduate School Of Ve
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Ito Mutsumi
Laboratory Of Microbiology Department Of Disease Control School Of Veterinary Medicine Hokkaido Univ
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Kida Hiroshi
Laboratory Of Microbiology Department Of Disease Control Graduate School Of Veterinary Medicine Hokk
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Naito Michiko
Department Of Disease Control Graduate School Of Veterinary Medicine Hokkaido University
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Isoda Norikazu
Laboratory Of Microbiology Department Of Disease Control School Of Veterinary Medicine Hokkaido Univ
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NAITO Michiko
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060–0818, Japan
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ITO Yuki
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060–0818, Japan
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ISODA Norikazu
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
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ITO Yuki
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
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SAKODA Yoshihiro
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
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UMEMURA Takashi
Laboratory of Comparative Pathology, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University
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ITO Mutsumi
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
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TANAKA Tomohisa
Laboratory of Comparative Pathology, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University
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NAITO Michiko
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
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